Abstract：
Scalp psoriasis is a common manifestation of psoriasis that significantly impacts a patient\'s quality of life. About 80% of cases of psoriasis involve the scalp, making it the most frequently affected area of the body. The treatment of scalp psoriasis is particularly crucial because of its hard-to-treat nature and substantial adverse impacts on overall well-being. Along with the physical symptoms of discomfort and itching, psoriasis, especially when it affects the scalp, can cause severe psychological damage. Treating scalp psoriasis can be challenging due to its location and associated symptoms, such as scaling and pruritus, which is why various drugs have become widely used for refractory cases. Topical treatments like corticosteroids and vitamin D analogs manage scalp psoriasis by reducing inflammation and regulating skin cell growth. Tar-based shampoos, salicylic acid solutions, and moisturizers control scaling. Phototherapy with UVB light reduces inflammation. Severe cases may require systemic medications such as oral retinoids and immunosuppressants. While various therapies are accessible for scalp psoriasis, concerns arise due to their limited advantages and the absence of controlled studies assessing their effectiveness. Considering these challenges, there is a clear demand for innovative approaches to address this condition effectively. Recent advancements in topical therapies, phototherapy, systemic agents, and complementary therapies have shown promising results in managing scalp psoriasis. Also, the advent of biologics, specifically anti-IL-17 and anti-IL-23 drugs for scalp psoriasis, has seen significant improvements. The review highlights the lack of well-tolerated and effective treatments for scalp psoriasis and underscores the importance of further research in this area. The objective of this review is to clarify the different treatment options currently available or being investigated in clinical trials for managing scalp psoriasis.
摘要：
头皮牛皮癣是牛皮癣的常见表现，显著影响患者的生活质量。大约80％的牛皮癣病例涉及头皮，使其成为身体最常受影响的区域。头皮牛皮癣的治疗特别重要，因为其难以治疗的性质和对总体健康的重大不利影响。伴随着身体不适和瘙痒的症状，牛皮癣,尤其是当它影响头皮时，会造成严重的心理伤害。由于其位置和相关症状，治疗头皮牛皮癣可能具有挑战性，如鳞屑和瘙痒，这就是为什么各种药物被广泛用于难治性病例。皮质类固醇和维生素D类似物等局部治疗通过减少炎症和调节皮肤细胞生长来管理头皮牛皮癣。焦油洗发水,水杨酸溶液,和保湿剂控制缩放。用UVB光进行光疗可减少炎症。严重病例可能需要全身性药物治疗，如口服类维生素A和免疫抑制剂。虽然头皮牛皮癣可以获得各种疗法，由于其有限的优势和缺乏评估其有效性的对照研究，引起了人们的关注。考虑到这些挑战,显然需要创新方法来有效解决这一问题。局部疗法的最新进展，光疗,全身性药物，和补充疗法在治疗头皮牛皮癣方面显示出有希望的结果。此外，生物制剂的出现，特别是抗IL-17和抗IL-23药物用于头皮牛皮癣，已经看到了显著的改进。该综述强调了头皮牛皮癣缺乏良好的耐受性和有效的治疗方法，并强调了该领域进一步研究的重要性。本综述的目的是阐明目前可用或正在临床试验中研究的治疗头皮银屑病的不同治疗方案。
