PDF(Pubmed)
Abstract：
OBJECTIVE: The external oblique intercostal plane (EOI) block is a novel block technique for anterolateral upper abdominal wall analgesia. The superficial nature of the external oblique intercostal plane allows it to be easily identified even in patients with obesity. The aim of this study was to test the hypothesis that EOI block would reduce IV morphine consumption within 24 h after laparoscopic sleeve gastrectomy.
METHODS: Patients were randomly assigned to one of two groups: EOI block group and control group. The patients in the EOI block group received ultrasound-guided bilateral EOI block with a total of 40 ml 0.25% bupivacaine after anesthesia induction. The patients in the control group received no intervention. Postoperatively, all the patients were connected to an intravenous patient controlled analgesia (PCA) device containing morphine. The primary outcome of the study was IV morphine consumption in the first postoperative 24 h.
RESULTS: The median [interquartile range] morphine consumption at 24 h postoperatively was significantly lower in the EOI block group than in the control group (7.5 [3.5 to 8.5] mg vs 14 [12 to 20] mg, p = 0.0001, respectively). Numerical rating scale (NRS) scores at rest and during movement were lower in the EOI block group than in the control group at 2, 6, and 12 h but were similar at 24 h. No block-related complications were observed in any patients.
CONCLUSIONS: The results of the current study demonstrated that bilateral EOI block reduced postoperative opioid consumption and postoperative pain in patients with obesity undergoing laparoscopic sleeve gastrectomy.
BACKGROUND: Clinicaltrials.gov identifier: NCT05663658.
METHODS: Patients were randomly assigned to one of two groups: EOI block group and control group. The patients in the EOI block group received ultrasound-guided bilateral EOI block with a total of 40 ml 0.25% bupivacaine after anesthesia induction. The patients in the control group received no intervention. Postoperatively, all the patients were connected to an intravenous patient controlled analgesia (PCA) device containing morphine. The primary outcome of the study was IV morphine consumption in the first postoperative 24 h.
RESULTS: The median [interquartile range] morphine consumption at 24 h postoperatively was significantly lower in the EOI block group than in the control group (7.5 [3.5 to 8.5] mg vs 14 [12 to 20] mg, p = 0.0001, respectively). Numerical rating scale (NRS) scores at rest and during movement were lower in the EOI block group than in the control group at 2, 6, and 12 h but were similar at 24 h. No block-related complications were observed in any patients.
CONCLUSIONS: The results of the current study demonstrated that bilateral EOI block reduced postoperative opioid consumption and postoperative pain in patients with obesity undergoing laparoscopic sleeve gastrectomy.
BACKGROUND: Clinicaltrials.gov identifier: NCT05663658.
摘要：
目的：外斜肋间平面（EOI）阻滞是一种用于上腹壁前外侧镇痛的新型阻滞技术。外斜肋间平面的表面性质使其即使在肥胖患者中也易于识别。这项研究的目的是检验以下假设：EOI阻滞会在腹腔镜袖状胃切除术后24小时内减少静脉吗啡的消耗。
方法：患者随机分为两组：EOI阻滞组和对照组。EOI阻滞组患者麻醉诱导后接受超声引导双侧EOI阻滞，共40ml0.25%布比卡因。对照组患者不接受干预。术后,所有患者均连接到含有吗啡的静脉患者自控镇痛(PCA)装置.该研究的主要结果是术后24小时内的静脉注射吗啡。
结果：EOI阻滞组术后24小时的吗啡消耗中位数[四分位数范围]显着低于对照组（7.5[3.5至8.5]mgvs14[12至20]mg，分别为p=0.0001)。在2、6和12h时，EOI阻滞组的静息和运动过程中的数字评分（NRS）评分低于对照组，但在24h时相似。在任何患者中均未观察到与阻滞相关的并发症。
结论：目前的研究结果表明，双侧EOI阻滞可减少肥胖患者腹腔镜袖状胃切除术后的阿片类药物消耗和术后疼痛。
背景：Clinicaltrials.gov标识符：NCT05663658。
方法：患者随机分为两组：EOI阻滞组和对照组。EOI阻滞组患者麻醉诱导后接受超声引导双侧EOI阻滞，共40ml0.25%布比卡因。对照组患者不接受干预。术后,所有患者均连接到含有吗啡的静脉患者自控镇痛(PCA)装置.该研究的主要结果是术后24小时内的静脉注射吗啡。
结果：EOI阻滞组术后24小时的吗啡消耗中位数[四分位数范围]显着低于对照组（7.5[3.5至8.5]mgvs14[12至20]mg，分别为p=0.0001)。在2、6和12h时，EOI阻滞组的静息和运动过程中的数字评分（NRS）评分低于对照组，但在24h时相似。在任何患者中均未观察到与阻滞相关的并发症。
结论：目前的研究结果表明，双侧EOI阻滞可减少肥胖患者腹腔镜袖状胃切除术后的阿片类药物消耗和术后疼痛。
背景：Clinicaltrials.gov标识符：NCT05663658。
