关键词: Antibiotic duration Cellulitis Erysipelas Guidelines Skin and soft tissue infection

Mesh : Adult Humans Anti-Bacterial Agents / therapeutic use Erysipelas / drug therapy Soft Tissue Infections / drug therapy diagnosis Retrospective Studies Controlled Before-After Studies Prescriptions Hospitals, University

来  源:   DOI:10.1016/j.idnow.2024.104887

Abstract:
BACKGROUND: New skin and soft tissue infections (SSTI) guidelines were published in 2019 in France, changing the recommended duration for antibiotic treatment. The objective of the present study was to assess the impact of the publication of the 2019 French guidelines on SSTIs on the duration of antibiotic prescription for erysipelas.
METHODS: In a before-after study (a year before and a year after April 1st, 2019), we included all adult patients diagnosed with erysipelas in Reims University Hospital medical wards and the emergency department. We retrospectively retrieved antibiotic prescription duration in the patients\' medical files.
RESULTS: Among 50 patients in the \"before\" and 39 in the \"after\" group, the mean duration of antibiotic prescription was significantly shorter in the \"after\" group (9.4 ± 2.8 vs. 12.4 ± 3.8 days, p = 0.0001).
CONCLUSIONS: A 25% decrease in the duration of antibiotic prescription for erysipelas was observed following the implementation of these guidelines, providing useful information for an antibiotic stewardship policy.
摘要:
背景:2019年在法国发布了新的皮肤和软组织感染(SSTI)指南,改变抗生素治疗的推荐持续时间。本研究的目的是评估2019年法国SSTIs指南的发布对丹毒抗生素处方持续时间的影响。
方法:在一项前后研究中(4月1日之前一年和之后一年,2019),我们纳入了兰斯大学医院内科病房和急诊科所有确诊为丹毒的成年患者.我们回顾性检索了患者医疗档案中的抗生素处方持续时间。
结果:在“之前”组中的50名患者和“之后”组中的39名患者中,在“后”组中,抗生素处方的平均持续时间显着缩短(9.4±2.8vs.12.4±3.8天,p=0.0001)。
结论:实施这些指南后,丹毒抗生素处方的持续时间减少了25%,为抗生素管理政策提供有用的信息。
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