Abstract：
Frailty is prevalent in elderly cardiac patients and may be a critical predictor of post-operative neurocognitive disorders (PND). The aim of this review was to demonstrate the correlation of frailty with PND in postsurgical elder patients. A review of published literature and bibliometric analysis was undertaken. Electronic databases from 2009 to 2022 were searched to identify articles that evaluated the relationship between frailty and PND in aging populations. Demographic data, type of surgery performed, frailty measurement, and impact of frailty on PND were extracted from the selected studies. The quality of the studies and risk of bias were assessed by the Newcastle-Ottawa Quality Assessment Scale, and the included articles were assessed as medium to high quality. Eighty-one studies were selected for the Bibliometric review in terms of research trends and hotpots. Additionally, 35 observational studies (prospective and retrospective cohorts) were selected for this review. The mean age ranged from 63 to 84 years and included patients undergoing cardiac, orthopedic, and other surgeries who had cardiac symptoms. Regardless of how frailty was measured, the strongest evidence in terms of numbers of studies, consistency of results, and study quality was for associations between frailty and PND. This analysis found a steadily growing focus on frailty and PND research in cardiac and other patients. The observational studies account for the majority of this area, and frailty occurred in the older cardiac patients over 60 years of age, and pre-screening of frailty can be predictive of PND and mortality.
摘要：
衰弱在老年心脏病患者中普遍存在，可能是术后神经认知障碍（PND）的关键预测指标。这篇综述的目的是证明老年患者术后虚弱与PND的相关性。对已发表的文献和文献计量分析进行了回顾。搜索了2009年至2022年的电子数据库，以确定评估衰老人群中虚弱与PND之间关系的文章。人口统计数据,进行的手术类型，脆弱的测量，并从选定的研究中提取虚弱对PND的影响。通过纽卡斯尔-渥太华质量评估量表评估研究质量和偏倚风险。纳入的文章被评估为中到高质量。根据研究趋势和热点，选择了81项研究进行文献计量学综述。此外,本综述选择了35项观察性研究（前瞻性和回顾性队列）。平均年龄为63至84岁，包括接受心脏手术的患者，骨科,和其他有心脏症状的手术。不管测量多么脆弱，就研究数量而言，最有力的证据是，结果的一致性，研究质量是针对虚弱和PND之间的关联。这项分析发现，心脏病和其他患者的衰弱和PND研究越来越受到关注。观测研究占了这一领域的大部分，和衰弱发生在60岁以上的老年心脏病患者中，和虚弱的预筛查可以预测PND和死亡率。
