关键词: EN 14476 Influenza virus Oral rinse Plant oils Quantitative suspension test SARS-CoV-2, RSV

Mesh : Humans Mouthwashes / pharmacology SARS-CoV-2 / drug effects Plant Oils / pharmacology Antiviral Agents / pharmacology Virus Inactivation / drug effects Respiratory Syncytial Viruses / drug effects COVID-19 / prevention & control

来  源:   DOI:10.1016/j.jhin.2024.02.023

Abstract:
BACKGROUND: Respiratory viruses have been reported to infect the salivary glands and the throat, which are potential reservoirs for virus replication and transmission. Therefore, strategies to reduce the amount of infective virus particles in the oral mucous membranes could lower the risk of transmission.
METHODS: The viral inactivation capacity of a plant-oil-based oral rinse (Salviathymol®) was evaluated in comparison with chlorhexidine (Chlorhexamed® FORTE) using a quantitative suspension test according to EN 14476.
RESULTS: Salviathymol efficiently inactivated severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), respiratory syncytial virus (RSV) and two influenza strains to undetectable levels.
CONCLUSIONS: Salviathymol has potential as preventive measure to lower transmission of respiratory viruses.
摘要:
据报道,呼吸道病毒感染唾液腺和咽喉,是病毒复制和传播的潜在储库。因此,减少口腔粘膜中感染性病毒颗粒数量的策略可以降低传播风险.在这项研究中,根据EN14476的定量悬浮试验,与氯己定(氯己酮FORTE)相比,评估了植物油型口腔冲洗液(Salviathymol)的病毒灭活能力.丹参醇可有效灭活严重急性呼吸综合征冠状病毒2型(SARS-CoV-2),呼吸道合胞病毒(RSV)和两种流感病毒株检测不到的水平,强调其作为降低呼吸道病毒传播的预防措施的潜力。
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