METHODS: A systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals were calculated.
RESULTS: Four studies were identified, involving a total of 1626 cases (Drain: n = 1251, no Drain: n = 375). There was a statistically significant difference noted between the 2 groups regarding postoperative seroma formation favoring the Drain group (odds ratio = 0.12; 95% confidence intervals [0.05, 0.29]; P < .001; 4 studies; I2 = 72%). For the remaining secondary endpoints postoperative urinary retention, recurrence, mesh infection and in-hospital length of stay no statistically significant difference was noted between the 2 study groups.
CONCLUSIONS: Current evidence suggests that patients who underwent TEP with routine closed-suction drain placement developed significantly fewer seromas without any additional morbidity or prolongation of in-hospital stay.
方法:进行了系统的文献检索,以比较有或没有常规引流的TEP结果。提取有关术后结果的数据,并通过荟萃分析进行比较。计算比值比和95%置信区间的标准化平均差。
结果:确定了四项研究,共1626例(排水:n=1251,无排水:n=375)。在术后血清肿形成方面,两组之间存在统计学上的显着差异,有利于Drain组(比值比=0.12;95%置信区间[0.05,0.29];P<.001;4项研究;I2=72%)。对于术后尿潴留的其余次要终点,复发,2个研究组间网片感染和住院时间无统计学差异.
结论:目前的证据表明,行TEP并进行常规闭式引流的患者出现的血清瘤明显减少,没有任何额外的发病率或住院时间延长。