PDF(Pubmed)
Abstract：
Anaplastic large-cell lymphoma (ALCL) is a subtype of T-cell lymphoma. This disease mainly affects lymph nodes, although extranodal sites may also be involved. Lymphoma in the pancreas is a rare clinical entity whether it manifests as primary or extranodal involvement. We discuss an unusual case of a 29-year-old male patient who presented with epigastric pain and a right neck mass. The patient\'s symptoms, physical examination, and laboratory tests prompted further investigation using imaging modalities such as CT, MRI, and endoscopic ultrasound, which revealed the presence of soft tissue masses in the right supraclavicular region and an ill-defined lesion within the pancreatic head. These findings eventually led to the identification of secondary extranodal pancreatic lymphoma. Fine needle biopsy (FNB) established an ultimate diagnosis of anaplastic lymphoma kinase (ALK)-positive ALCL.
摘要：
间变性大细胞淋巴瘤（ALCL）是T细胞淋巴瘤的一种亚型。这种疾病主要影响淋巴结，尽管也可能涉及结外部位。胰腺中的淋巴瘤是一种罕见的临床实体，无论是表现为原发性还是结外受累。我们讨论了一名29岁男性患者的不寻常病例，该患者表现为上腹痛和右颈部肿块。病人的症状,体检,和实验室测试促使进一步调查使用成像方式，如CT，MRI,还有超声内镜,显示右侧锁骨上区域存在软组织肿块，胰头内存在不明确的病变。这些发现最终导致了继发性结外胰腺淋巴瘤的鉴定。细针活检（FNB）确定了间变性淋巴瘤激酶（ALK）阳性ALCL的最终诊断。
