PDF(Pubmed)
Abstract：
UNASSIGNED: Medulloblastoma, a highly malignant embryonal tumor predominantly found in the pediatric population, typically arises within the cerebellum. This case report holds particular importance due to the rarity of medulloblastoma within the cerebellopontine angle (CPA). The distinct anatomical challenge posed by the CPA complex neurovascular structures, along with the absence of pathognomonic clinical or radiographic features, highlights the unique diagnostic and management challenge of this case.
UNASSIGNED: A 5-year-old boy presented with mild, progressively worsening headaches on CT/MRI imaging, which revealed a solid mass in the left CPA. Radiologically, the lesion closely resembled a CPA meningioma. The patient underwent a left retrosigmoid suboccipital craniectomy, utilizing a modified park bench position and careful burrhole creation. Intraoperatively, the tumor exhibited well-defined margins, firm adherence to cranial nerves, and complex tissue characteristics. Postoperatively, histopathological analysis identified nodular medulloblastoma, WHO grade IV, with immunohistochemical markers confirming its subtype.
UNASSIGNED: This case highlights the critical role of surgical intervention in addressing rare tumors, emphasizing the need for multidisciplinary collaboration in both diagnosis and management to achieve a favorable outcome. Uncommon tumor locations, such as the CPA, require tailored approaches, and the utilization of advanced diagnostic techniques, including immunohistochemistry, aids in accurate subtype classification.
UNASSIGNED: This case highlights the critical role of surgical intervention in addressing rare tumors, emphasizing the need for multidisciplinary collaboration in both diagnosis and management to achieve a favorable outcome.
UNASSIGNED: A 5-year-old boy presented with mild, progressively worsening headaches on CT/MRI imaging, which revealed a solid mass in the left CPA. Radiologically, the lesion closely resembled a CPA meningioma. The patient underwent a left retrosigmoid suboccipital craniectomy, utilizing a modified park bench position and careful burrhole creation. Intraoperatively, the tumor exhibited well-defined margins, firm adherence to cranial nerves, and complex tissue characteristics. Postoperatively, histopathological analysis identified nodular medulloblastoma, WHO grade IV, with immunohistochemical markers confirming its subtype.
UNASSIGNED: This case highlights the critical role of surgical intervention in addressing rare tumors, emphasizing the need for multidisciplinary collaboration in both diagnosis and management to achieve a favorable outcome. Uncommon tumor locations, such as the CPA, require tailored approaches, and the utilization of advanced diagnostic techniques, including immunohistochemistry, aids in accurate subtype classification.
UNASSIGNED: This case highlights the critical role of surgical intervention in addressing rare tumors, emphasizing the need for multidisciplinary collaboration in both diagnosis and management to achieve a favorable outcome.
摘要：
■髓母细胞瘤,一种主要在儿科人群中发现的高度恶性胚胎性肿瘤，通常出现在小脑内。由于桥小脑角（CPA）内髓母细胞瘤的罕见性，该病例报告尤为重要。由CPA复杂的神经血管结构构成的独特的解剖学挑战，伴随着缺乏病理的临床或影像学特征，突出了这种情况下独特的诊断和管理挑战。
■一个5岁的男孩，在CT/MRI成像上逐渐恶化的头痛，这显示了左边注册会计师的固体质量。放射学上,病变非常类似于CPA脑膜瘤。患者接受了左乙状结肠枕下后颅骨切除术，利用修改后的公园长凳位置和仔细的钻孔创建。术中,肿瘤表现出明确的边缘，牢牢坚持脑神经，和复杂的组织特征。术后,组织病理学分析确定结节性髓母细胞瘤，世卫组织四级，免疫组织化学标记证实其亚型。
这个案例突出了手术干预在解决罕见肿瘤方面的关键作用，强调需要在诊断和管理方面进行多学科合作，以取得有利的结果。罕见的肿瘤位置，比如注册会计师，需要量身定制的方法，利用先进的诊断技术，包括免疫组织化学,有助于准确的亚型分类。
这个案例突出了手术干预在解决罕见肿瘤方面的关键作用，强调需要在诊断和管理方面进行多学科合作，以取得有利的结果。
■一个5岁的男孩，在CT/MRI成像上逐渐恶化的头痛，这显示了左边注册会计师的固体质量。放射学上,病变非常类似于CPA脑膜瘤。患者接受了左乙状结肠枕下后颅骨切除术，利用修改后的公园长凳位置和仔细的钻孔创建。术中,肿瘤表现出明确的边缘，牢牢坚持脑神经，和复杂的组织特征。术后,组织病理学分析确定结节性髓母细胞瘤，世卫组织四级，免疫组织化学标记证实其亚型。
这个案例突出了手术干预在解决罕见肿瘤方面的关键作用，强调需要在诊断和管理方面进行多学科合作，以取得有利的结果。罕见的肿瘤位置，比如注册会计师，需要量身定制的方法，利用先进的诊断技术，包括免疫组织化学,有助于准确的亚型分类。
这个案例突出了手术干预在解决罕见肿瘤方面的关键作用，强调需要在诊断和管理方面进行多学科合作，以取得有利的结果。
