PDF(Pubmed)
Abstract：
Recent medical advancements have increased life expectancy, leading to a surge in patients affected by multiple chronic diseases and consequent polypharmacy, especially among older adults. This scenario increases the risk of drug interactions and adverse drug reactions, highlighting the need for medication review and deprescribing to reduce inappropriate medications and optimize therapeutic regimens, with the ultimate goal to improving patients\' health and quality of life. This position statement from the Italian Scientific Consortium on medication review and deprescribing aims to describe key elements, strategies, tools, timing, and healthcare professionals to be involved, for the implementation of medication review and deprescribing in different healthcare settings (i.e., primary care, hospital, long-term care facilities, and palliative care). Challenges and potential solutions for the implementation of medication review and deprescribing are also discussed.
摘要：
最近的医疗进步增加了预期寿命，导致受多种慢性疾病和随之而来的多重用药影响的患者激增，尤其是老年人。这种情况会增加药物相互作用和药物不良反应的风险，强调需要进行药物审查和取消处方，以减少不适当的药物和优化治疗方案，最终目标是改善患者的健康和生活质量。意大利科学联盟关于药物审查和开药的立场声明旨在描述关键要素，战略,工具,定时,和医疗保健专业人员参与，在不同的医疗保健环境中实施药物审查和取消处方(即，初级保健,医院,长期护理设施，和姑息治疗)。还讨论了实施药物审查和开处方的挑战和潜在解决方案。
