PDF(Pubmed)
Abstract：
Spinal infection caused by Parvimonas micra (P. micra) is a rare infection. The characteristic imageology includes spondylodiscitis, spondylitis, paravertebral abscess, and epidural abscess. One case of spondylodiscitis of lumbar complicated with spinal epidural abscess caused by P. micra was admitted to the Department of Spinal Surgery, Xiangya Hospital, Central South University on February, 2023. This case is a 60 years old man with lower back pain and left lower limb numbness. MRI showed spondylitis, spondylodiscitis, and epidural abscess. The patient underwent debridement, decompression and fusion surgery. The culture of surgical sample was negative. P. micra was detected by metagenomic next-generation sequencing (mNGS). The postoperative antibiotic treatment included intravenous infusion of linezolid and piperacillin for 1 week, then intravenous infusion of ceftazidime and oral metronidazole for 2 weeks, followed by oral metronidazole and nerofloxacin for 2 weeks. During the follow-up, the lower back pain and left lower limb numbness was complete remission. Spinal infection caused by P. micra is extremely rare, when the culture is negative, mNGS can help the final diagnosis.
微小小单胞菌引起的脊柱感染罕见，其影像学表现为椎间盘炎、脊椎炎、椎旁脓肿和硬膜外脓肿。中南大学湘雅医院于2023年2月收治1例微小小单胞菌腰椎间盘炎并椎管内硬膜外脓肿患者。患者为60岁男性，临床表现为腰痛伴左下肢麻木，MRI表现为脊椎炎、椎间盘炎、硬膜外脓肿。行脊柱病灶清除及减压融合术，手术标本培养为阴性，手术标本宏基因组二代测序(metagenomic next-generation sequencing，mNGS)检测结果为微小小单胞菌。术后静脉滴注利奈唑胺和哌拉西林1周，静脉滴注头孢他啶和口服甲硝唑2周，随后口服甲硝唑和奈诺沙星2周。在随访过程中，患者腰痛及左下肢麻木完全缓解。微小小单胞菌脊柱感染极为罕见，当培养结果呈阴性时，mNGS检测有助于最终明确诊断。.
微小小单胞菌引起的脊柱感染罕见，其影像学表现为椎间盘炎、脊椎炎、椎旁脓肿和硬膜外脓肿。中南大学湘雅医院于2023年2月收治1例微小小单胞菌腰椎间盘炎并椎管内硬膜外脓肿患者。患者为60岁男性，临床表现为腰痛伴左下肢麻木，MRI表现为脊椎炎、椎间盘炎、硬膜外脓肿。行脊柱病灶清除及减压融合术，手术标本培养为阴性，手术标本宏基因组二代测序(metagenomic next-generation sequencing，mNGS)检测结果为微小小单胞菌。术后静脉滴注利奈唑胺和哌拉西林1周，静脉滴注头孢他啶和口服甲硝唑2周，随后口服甲硝唑和奈诺沙星2周。在随访过程中，患者腰痛及左下肢麻木完全缓解。微小小单胞菌脊柱感染极为罕见，当培养结果呈阴性时，mNGS检测有助于最终明确诊断。.
摘要：
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