Abstract：
BACKGROUND: Ovarian fibromas are benign tumors that can present peculiar morphological features not studied sufficiently.
METHODS: In this retrospective study, 75 consecutive cases of ovarian fibroma were morphologically compared with 46 thecomas, 16 granulosa cell tumors, and 5 sclerosing stroma tumors for the following factors: the growth pattern as diffuse or nodular, the presence of hyaline plaques, necrosis, keloid-like sclerosis, calcifications, cystic degeneration, fibrous or edematous stroma, prominent vascularity, lutein cells, cellularity, scant or abundant cytoplasm, prominent cell membranes, nuclear grooves, atypia, and mitotic activity.
RESULTS: The tumors differed significantly in terms of hyaline plaques presence, nuclear grooves, growth pattern, stroma type, tumor cellularity, cytoplasm, prominence of cell membranes, atypia, mitotic activity, and prominent vascularity.
CONCLUSIONS: Ovarian fibromas can present some maybe unexpected features rather frequently, such as cystic degeneration, hyaline plaques, prominent vascularity, increased cellularity, and some mitotic activity, thus their presence should not always prompt to an alternative diagnosis.
METHODS: In this retrospective study, 75 consecutive cases of ovarian fibroma were morphologically compared with 46 thecomas, 16 granulosa cell tumors, and 5 sclerosing stroma tumors for the following factors: the growth pattern as diffuse or nodular, the presence of hyaline plaques, necrosis, keloid-like sclerosis, calcifications, cystic degeneration, fibrous or edematous stroma, prominent vascularity, lutein cells, cellularity, scant or abundant cytoplasm, prominent cell membranes, nuclear grooves, atypia, and mitotic activity.
RESULTS: The tumors differed significantly in terms of hyaline plaques presence, nuclear grooves, growth pattern, stroma type, tumor cellularity, cytoplasm, prominence of cell membranes, atypia, mitotic activity, and prominent vascularity.
CONCLUSIONS: Ovarian fibromas can present some maybe unexpected features rather frequently, such as cystic degeneration, hyaline plaques, prominent vascularity, increased cellularity, and some mitotic activity, thus their presence should not always prompt to an alternative diagnosis.
摘要：
背景：卵巢纤维瘤是良性肿瘤，可能存在特殊的形态学特征，但未得到充分研究。
方法：在这项回顾性研究中，连续75例卵巢纤维瘤与46例卵巢纤维瘤进行形态学比较，16个颗粒细胞瘤，和5硬化性间质瘤为以下因素：生长模式为弥漫性或结节性，透明斑块的存在，坏死,瘢痕疙瘩样硬化,钙化,囊性变性,纤维状或水肿间质，突出的血管，叶黄素细胞,cellularity,很少或丰富的细胞质，突出的细胞膜，核沟,非典型,和有丝分裂活性。
结果：肿瘤在透明斑块方面存在显著差异，核沟,增长模式,基质类型,肿瘤细胞数量，细胞质，细胞膜的突出，非典型,有丝分裂活性，和突出的血管。
结论：卵巢纤维瘤可以表现出一些意想不到的特征，如囊性变性，透明斑块,突出的血管，细胞增加，和一些有丝分裂活性，因此，他们的存在不应该总是提示另一种诊断。
方法：在这项回顾性研究中，连续75例卵巢纤维瘤与46例卵巢纤维瘤进行形态学比较，16个颗粒细胞瘤，和5硬化性间质瘤为以下因素：生长模式为弥漫性或结节性，透明斑块的存在，坏死,瘢痕疙瘩样硬化,钙化,囊性变性,纤维状或水肿间质，突出的血管，叶黄素细胞,cellularity,很少或丰富的细胞质，突出的细胞膜，核沟,非典型,和有丝分裂活性。
结果：肿瘤在透明斑块方面存在显著差异，核沟,增长模式,基质类型,肿瘤细胞数量，细胞质，细胞膜的突出，非典型,有丝分裂活性，和突出的血管。
结论：卵巢纤维瘤可以表现出一些意想不到的特征，如囊性变性，透明斑块,突出的血管，细胞增加，和一些有丝分裂活性，因此，他们的存在不应该总是提示另一种诊断。
