PDF(Pubmed)
Abstract：
UNASSIGNED: The objectives of this study were to (i) evaluate the prevalence of pre-iridal monocellular and fibrovascular membranes in canine globes affected with congenital glaucoma associated with anterior segment dysgenesis (ASD), primary glaucoma associated with goniodysgenesis (GD), and secondary glaucoma, and (ii) examine the associations between monocellular and fibrovascular membranes by breed, gender, age and histopathologic ocular changes on light microscopic examination.
UNASSIGNED: Records of dogs who had eyes enucleated due to blindness and uncontrolled glaucoma were reviewed. Glaucoma was categorized clinically and histologically into three groups: congenital/ASD, primary/GD, and secondary glaucoma. The presence or absence and type of pre-iridal membrane (monocellular or fibrovascular) and other intraocular histologic findings were reviewed and compared statistically for each group.
UNASSIGNED: In total, 108 canine globes (101 dogs) were included. Pre-iridal monocellular membranes were identified with light microscopy in 10 out of 19 congenital/ASD, 29 out of 40 primary, and 23 out of 49 secondary glaucoma globes. Fibrovascular membranes were observed in 3 out of 19 congenital/ASD, 9 out of 40 in primary, and 24 out of 49 secondary glaucoma globes. There were no associations between the type of membrane and breed, gender, or age. Peripheral anterior synechiae were more common in globes with fibrovascular membranes, and uveal atrophy was more common in globes with monocellular membranes.
UNASSIGNED: Pre-iridal monocellular membranes are common in all types of canine glaucoma. They are identified with light microscopy most easily in cases of primary glaucoma, and they are masked by pre-iridal fibrovascular membranes in other forms of glaucoma.
UNASSIGNED: Records of dogs who had eyes enucleated due to blindness and uncontrolled glaucoma were reviewed. Glaucoma was categorized clinically and histologically into three groups: congenital/ASD, primary/GD, and secondary glaucoma. The presence or absence and type of pre-iridal membrane (monocellular or fibrovascular) and other intraocular histologic findings were reviewed and compared statistically for each group.
UNASSIGNED: In total, 108 canine globes (101 dogs) were included. Pre-iridal monocellular membranes were identified with light microscopy in 10 out of 19 congenital/ASD, 29 out of 40 primary, and 23 out of 49 secondary glaucoma globes. Fibrovascular membranes were observed in 3 out of 19 congenital/ASD, 9 out of 40 in primary, and 24 out of 49 secondary glaucoma globes. There were no associations between the type of membrane and breed, gender, or age. Peripheral anterior synechiae were more common in globes with fibrovascular membranes, and uveal atrophy was more common in globes with monocellular membranes.
UNASSIGNED: Pre-iridal monocellular membranes are common in all types of canine glaucoma. They are identified with light microscopy most easily in cases of primary glaucoma, and they are masked by pre-iridal fibrovascular membranes in other forms of glaucoma.
摘要：
■这项研究的目的是（i）评估患有与前节发育不全（ASD）相关的先天性青光眼的犬眼球中虹膜前单核细胞和纤维血管膜的患病率，原发性青光眼与性腺发育（GD）相关，和继发性青光眼，（ii）按品种检查单核细胞和纤维血管膜之间的关联，性别,光学显微镜检查的年龄和组织病理学眼部变化。
■回顾了由于失明和未控制的青光眼而导致眼睛摘除的狗的记录。青光眼在临床和组织学上分为三组：先天性/ASD，初级/GD,和继发性青光眼。对各组的虹膜前膜（单核细胞或纤维血管）的存在与否和类型以及其他眼内组织学发现进行了回顾和统计学比较。
■总共，包括108只犬球(101只狗)。在19例先天性/ASD中，有10例通过光学显微镜鉴定出虹膜前单核细胞膜，40个小学中有29个，49个继发性青光眼球中有23个。在19例先天性/ASD中观察到3例血管膜，小学40人中有9人，49个继发性青光眼球中有24个。膜的类型和品种之间没有关联，性别,或年龄。外周前粘连在有纤维血管膜的球体中更常见，葡萄膜萎缩在具有单细胞膜的球体中更为常见。
■前虹膜单细胞膜在所有类型的犬青光眼中都很常见。在原发性青光眼的情况下，最容易用光学显微镜识别它们，在其他形式的青光眼中，它们被虹膜前纤维血管膜掩盖。
■回顾了由于失明和未控制的青光眼而导致眼睛摘除的狗的记录。青光眼在临床和组织学上分为三组：先天性/ASD，初级/GD,和继发性青光眼。对各组的虹膜前膜（单核细胞或纤维血管）的存在与否和类型以及其他眼内组织学发现进行了回顾和统计学比较。
■总共，包括108只犬球(101只狗)。在19例先天性/ASD中，有10例通过光学显微镜鉴定出虹膜前单核细胞膜，40个小学中有29个，49个继发性青光眼球中有23个。在19例先天性/ASD中观察到3例血管膜，小学40人中有9人，49个继发性青光眼球中有24个。膜的类型和品种之间没有关联，性别,或年龄。外周前粘连在有纤维血管膜的球体中更常见，葡萄膜萎缩在具有单细胞膜的球体中更为常见。
■前虹膜单细胞膜在所有类型的犬青光眼中都很常见。在原发性青光眼的情况下，最容易用光学显微镜识别它们，在其他形式的青光眼中，它们被虹膜前纤维血管膜掩盖。
