关键词: Early recurrence Hepatectomy Hepatocellular carcinoma (HCC) Liver resection Microvascular invasion (MVI)

Mesh : Carcinoma, Hepatocellular / pathology surgery Humans Liver Neoplasms / surgery pathology Neoplasm Recurrence, Local / pathology Hepatectomy Neoplasm Invasiveness Microvessels / pathology Prognosis Time Factors

来  源:   DOI:10.1016/j.asjsur.2024.02.115

Abstract:
Hepatectomy is widely considered a potential treatment for hepatocellular carcinoma (HCC). Unfortunately, one-third of HCC patients have tumor recurrence within 2 years after surgery (early recurrence), accounting for more than 60% of all recurrence patients. Early recurrence is associated with a worse prognosis. Previous studies have shown that microvascular invasion (MVI) is one of the key factors for early recurrence and poor prognosis in patients with HCC after surgery. This paper reviews the latest literature and summarizes the predictors of MVI, the correlation between MVI and early recurrence, the identification of suspicious nodules or subclinical lesions, and the treatment strategies for MVI-positive HCC. The aim is to explore the management of patients with MVI-positive HCC.
摘要:
肝切除术被广泛认为是肝细胞癌(HCC)的潜在治疗方法。不幸的是,三分之一的HCC患者在手术后2年内有肿瘤复发(早期复发),占所有复发患者的60%以上。早期复发与预后较差相关。已有研究表明,微血管侵犯(MVI)是肝癌患者术后早期复发和预后不良的关键因素之一。本文回顾了最新的文献,总结了MVI的预测因素,MVI与早期复发的相关性,可疑结节或亚临床病变的识别,以及MVI阳性肝癌的治疗策略。目的是探讨MVI阳性HCC患者的治疗方法。
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