Abstract：
UNASSIGNED: The benefits of topical pharyngeal anesthesia for gastroscopy remain under debate. Articaine, a local anesthetic with fast onset and offset of action as well as low systemic toxicity, could be a promising choice for topical anesthesia. The objective of this study was to assess whether topical pharyngeal anesthesia with articaine is beneficial in sedated gastroscopy.
UNASSIGNED: This randomized double-blinded cross-over study included nine volunteers who underwent two gastroscopies under conscious sedation. One was performed with topical pharyngeal anesthesia with articaine and the other with placebo. Hemodynamic parameters including autonomic nervous system state were recorded prior to and during the endoscopic procedure. The endoscopist and the volunteer assessed the endoscopy after the examination.
UNASSIGNED: Topical pharyngeal anesthesia with articaine resulted in less discomfort during esophageal intubation and higher patient satisfaction with the procedure. Topical pharyngeal anesthesia with articaine did not increase satisfaction or facilitate the procedure as rated by the endoscopist. There were no clinically relevant differences in hemodynamic parameters.
UNASSIGNED: The use of articaine for topical pharyngeal anesthesia results in less intubation-related discomfort and better satisfaction.
UNASSIGNED: This randomized double-blinded cross-over study included nine volunteers who underwent two gastroscopies under conscious sedation. One was performed with topical pharyngeal anesthesia with articaine and the other with placebo. Hemodynamic parameters including autonomic nervous system state were recorded prior to and during the endoscopic procedure. The endoscopist and the volunteer assessed the endoscopy after the examination.
UNASSIGNED: Topical pharyngeal anesthesia with articaine resulted in less discomfort during esophageal intubation and higher patient satisfaction with the procedure. Topical pharyngeal anesthesia with articaine did not increase satisfaction or facilitate the procedure as rated by the endoscopist. There were no clinically relevant differences in hemodynamic parameters.
UNASSIGNED: The use of articaine for topical pharyngeal anesthesia results in less intubation-related discomfort and better satisfaction.
摘要：
■局部咽部麻醉用于胃镜检查的益处仍在争论中。阿替卡因,具有快速起效和抵消作用以及低全身毒性的局部麻醉药，可能是局部麻醉的一个有希望的选择。这项研究的目的是评估阿替卡因局部咽部麻醉在镇静胃镜检查中是否有益。
■这项随机双盲交叉研究包括9名志愿者，他们在清醒镇静下接受了两次胃镜检查。一种是用阿替卡因局部咽部麻醉，另一种是安慰剂。在内窥镜手术之前和期间记录了包括自主神经系统状态在内的血液动力学参数。内窥镜医师和志愿者在检查后评估内窥镜检查。
■阿替卡因局部咽部麻醉减少了食管插管时的不适感，提高了患者对手术的满意度。阿替卡因局部咽部麻醉并不能提高满意度，也不能促进内窥镜医师的评估。血液动力学参数没有临床相关差异。
■将阿替卡因用于局部咽部麻醉可减少与插管相关的不适感，提高满意度。
■这项随机双盲交叉研究包括9名志愿者，他们在清醒镇静下接受了两次胃镜检查。一种是用阿替卡因局部咽部麻醉，另一种是安慰剂。在内窥镜手术之前和期间记录了包括自主神经系统状态在内的血液动力学参数。内窥镜医师和志愿者在检查后评估内窥镜检查。
■阿替卡因局部咽部麻醉减少了食管插管时的不适感，提高了患者对手术的满意度。阿替卡因局部咽部麻醉并不能提高满意度，也不能促进内窥镜医师的评估。血液动力学参数没有临床相关差异。
■将阿替卡因用于局部咽部麻醉可减少与插管相关的不适感，提高满意度。
