Abstract：
UNASSIGNED: Hearing loss is important in the diagnosis and treatment of Meniere\'s disease (MD). However, little is known about the factors associated with hearing changes in MD.
UNASSIGNED: This study aimed to investigate the correlation between hearing prognosis and caloric test (CT) results in MD.
UNASSIGNED: Ninety consecutive patients diagnosed with unilateral definite MD underwent pure tone audiometry (PTA) and CT at initial visits, and were re-tested PTA at the 6-month follow-up.
UNASSIGNED: Fifty-three of ninety MD patients (58.89%) had abnormal CT results. The change of PTA (cPTA = initial PTA-last PTA) was negatively correlated with canal paresis (CP) values (overall association p = 0.032 and non-linear association p = 0.413). Multivariate linear model showed that as the CP value changed from 0 to 1, the cPTA decreased by -13.31 dB (95% CI: -24.03, -2.6) (p = 0.016). Stratified analysis found that the association was present in MD patients of Stage 1 and 2 (p < 0.05) but not in patients of Stage 3 and 4 (p > 0.05).
UNASSIGNED: Elevated CP values may be linked to worse hearing outcomes in MD, especially in Stage 1 and 2 patients. Conducting a caloric test at the initial consultation may aid in assessing hearing regression in MD.
UNASSIGNED: This study aimed to investigate the correlation between hearing prognosis and caloric test (CT) results in MD.
UNASSIGNED: Ninety consecutive patients diagnosed with unilateral definite MD underwent pure tone audiometry (PTA) and CT at initial visits, and were re-tested PTA at the 6-month follow-up.
UNASSIGNED: Fifty-three of ninety MD patients (58.89%) had abnormal CT results. The change of PTA (cPTA = initial PTA-last PTA) was negatively correlated with canal paresis (CP) values (overall association p = 0.032 and non-linear association p = 0.413). Multivariate linear model showed that as the CP value changed from 0 to 1, the cPTA decreased by -13.31 dB (95% CI: -24.03, -2.6) (p = 0.016). Stratified analysis found that the association was present in MD patients of Stage 1 and 2 (p < 0.05) but not in patients of Stage 3 and 4 (p > 0.05).
UNASSIGNED: Elevated CP values may be linked to worse hearing outcomes in MD, especially in Stage 1 and 2 patients. Conducting a caloric test at the initial consultation may aid in assessing hearing regression in MD.
摘要：
■听力损失在梅尼埃病（MD）的诊断和治疗中很重要。然而,对MD听力变化的相关因素知之甚少。
■本研究旨在调查MD的听力预后与热量测试（CT）结果之间的相关性。
■90例连续诊断为单侧明确MD的患者在初次就诊时接受了纯音测听（PTA）和CT检查，并在6个月随访时重新测试PTA。
■90例MD患者中有53例（58.89%）的CT结果异常。PTA（cPTA=初始PTA-最后PTA）的变化与管麻痹（CP）值呈负相关（总体关联p=0.032，非线性关联p=0.413）。多元线性模型显示，当CP值从0变为1时，cPTA下降了-13.31dB（95%CI：-24.03，-2.6）（p=0.016）。分层分析发现，在1期和2期的MD患者中存在相关性（p<0.05），而在3期和4期的患者中不存在相关性（p>0.05）。
■CP值升高可能与MD的听力结果恶化有关，尤其是1期和2期患者。在初次咨询时进行热量测试可能有助于评估MD的听力退化。
■本研究旨在调查MD的听力预后与热量测试（CT）结果之间的相关性。
■90例连续诊断为单侧明确MD的患者在初次就诊时接受了纯音测听（PTA）和CT检查，并在6个月随访时重新测试PTA。
■90例MD患者中有53例（58.89%）的CT结果异常。PTA（cPTA=初始PTA-最后PTA）的变化与管麻痹（CP）值呈负相关（总体关联p=0.032，非线性关联p=0.413）。多元线性模型显示，当CP值从0变为1时，cPTA下降了-13.31dB（95%CI：-24.03，-2.6）（p=0.016）。分层分析发现，在1期和2期的MD患者中存在相关性（p<0.05），而在3期和4期的患者中不存在相关性（p>0.05）。
■CP值升高可能与MD的听力结果恶化有关，尤其是1期和2期患者。在初次咨询时进行热量测试可能有助于评估MD的听力退化。
