Abstract：
A 70-year-old man who had undergone treatment for gastroesophageal reflux disease (GERD) by a family doctor presented to our hospital with severe heartburn and dysphagia despite taking vonoprazan (20 mg) for 3 months. A diagnosis of vonoprazan-refractory nonerosive reflux disease was made based on esophagogastroduodenoscopy and esophageal function examinations. The patient elected to undergo endoscopic treatment for GERD. Therefore, we performed endoscopic treatment using the endoscopic submucosal dissection (ESD-G) technique developed at our institution. After endoscopic treatment, his GERD symptoms disappeared and he no longer required GERD-related medications. An examination of his esophageal function revealed the improvement of items related to GERD.
摘要：
一名70岁的男子接受了家庭医生的胃食管反流病（GERD）治疗，尽管服用vonoprazan（20mg）3个月，但仍出现严重的胃灼热和吞咽困难。根据食管胃十二指肠镜检查和食管功能检查，诊断为vonoprazan难治性非糜烂性反流病。患者选择接受GERD的内镜治疗。因此,我们使用我们机构开发的内镜黏膜下剥离术(ESD-G)技术进行内镜治疗.内镜治疗后，他的GERD症状消失,他不再需要GERD相关药物治疗.检查他的食管功能显示与GERD相关的项目有所改善。
