METHODS: 457 patients with achalasia who underwent LHD as the primary surgery between September 2005 and December 2020 were included. We divided patients into the mGPS 0 and mGPS 1 or 2 groups and compared the patients\' background, pathophysiology, symptoms, surgical outcomes, and postoperative course.
RESULTS: mGPS was 0 in 379 patients and 1 or 2 in 78 patients. Preoperative vomiting and pneumonia were more common in patients with mGPS of 1 or 2. There were no differences in surgical outcomes. Postoperative upper gastrointestinal endoscopy revealed that severe esophagitis was more frequently observed in patients with mGPS of 1 or 2 (P < 0.01). The clinical success was 91% and 99% in the mGPS 0 and mGPS 1 or 2 groups, respectively (P < 0.01).
CONCLUSIONS: Although severe reflux esophagitis was more common in patients with achalasia with a high mGPS, good clinical success was obtained regardless of the preoperative mGPS.
方法:纳入了2005年9月至2020年12月间以LHD为主要手术的457例门失弛缓症患者。我们将患者分为mGPS0组和mGPS1或2组,并比较患者的背景,病理生理学,症状,手术结果,和术后过程。
结果:mGPS在379例患者中为0,在78例患者中为1或2。术前呕吐和肺炎在mGPS为1或2的患者中更为常见。手术结果无差异。术后上消化道内镜显示,mGPS为1或2的患者更容易观察到严重食管炎(P<0.01)。在mGPS0和mGPS1或2组中,临床成功率分别为91%和99%,分别为(P<0.01)。
结论:尽管严重反流性食管炎在高mGPS的门失弛缓症患者中更为常见,无论术前的mGPS如何,均获得了良好的临床成功。