Abstract：
Fibromatosis of the breast is a rare, benign locally infiltrative tumor without metastatic potential. Patients typically present with a painless, palpable, firm breast mass, which may be mobile or fixed to the pectoralis muscle. While some cases are related to familial mutations in the adenomatous polyposis coli (APC) gene, the majority are sporadic due to somatic mutations or prior injury to the breast tissue. On mammography, fibromatosis is typically seen as an irregular, dense, spiculated mass. US demonstrates a hypoechoic, irregular mass with indistinct margins. Fibromatosis is indistinguishable from breast cancer on imaging, and core biopsy is required for definitive diagnosis. Wide local excision is the historical standard for treatment; however, recurrence rates are high, and other emerging therapies are being explored. This article reviews the clinical features, imaging and histopathologic findings, along with brief overview of management.
摘要：
乳腺纤维瘤病是一种罕见的，良性局部浸润性肿瘤无转移潜力。患者通常表现为无痛，明显的，坚硬的乳房肿块,可以移动或固定在胸肌上。虽然有些病例与腺瘤性结肠息肉病（APC）基因的家族性突变有关，大多数是由于体细胞突变或乳房组织损伤而散发性。在乳房X线照相术上，纤维瘤病通常被视为不规则的，密集,针状肿块。美国表现出一种低回声，不规则的肿块，边缘不清楚。纤维瘤病在影像学上与乳腺癌无法区分，和核心活检需要明确的诊断。广泛的局部切除是治疗的历史标准；然而，复发率很高,和其他新兴疗法正在探索中。本文对其临床特点进行综述,影像学和组织病理学发现，以及管理的简要概述。
