{Reference Type}: Journal Article
{Title}: Breast Fibromatosis: Radiologic-Pathologic Correlation.
{Author}: Winkler N;Peterson M;Factor R;
{Journal}: J Breast Imaging
{Volume}: 3
{Issue}: 5
{Year}: 2021 Sep 16
暂无{DOI}: 10.1093/jbi/wbab051
{Abstract}: Fibromatosis of the breast is a rare, benign locally infiltrative tumor without metastatic potential. Patients typically present with a painless, palpable, firm breast mass, which may be mobile or fixed to the pectoralis muscle. While some cases are related to familial mutations in the adenomatous polyposis coli (APC) gene, the majority are sporadic due to somatic mutations or prior injury to the breast tissue. On mammography, fibromatosis is typically seen as an irregular, dense, spiculated mass. US demonstrates a hypoechoic, irregular mass with indistinct margins. Fibromatosis is indistinguishable from breast cancer on imaging, and core biopsy is required for definitive diagnosis. Wide local excision is the historical standard for treatment; however, recurrence rates are high, and other emerging therapies are being explored. This article reviews the clinical features, imaging and histopathologic findings, along with brief overview of management.