Abstract：
Eosinophilic esophagitis (EoE) is a chronic type 2-mediated inflammatory disease of the esophagus that represents the most common eosinophilic gastrointestinal disease. Experts in the field of EoE across Italy (i.e., EoETALY Consensus Group) including gastroenterologists, endoscopists, allergologists/immunologists, and paediatricians conducted a Delphi process to develop updated consensus statements for the management of patients with EoE and update the previous position paper of the Italian Society of Gastroenterology (SIGE) in light of recent evidence. Grading of the strength and quality of the evidence of the recommendations was performed using accepted GRADE criteria. The guideline is divided in two documents: Part 1 includes three chapters, namely 1) definition, epidemiology, and pathogenesis; 2) clinical presentation and natural history, and 3) diagnosis, while Part 2 includes two chapters: 4) treatment and 5) monitoring and follow-up. This document has received the endorsement of three Italian national societies including the SIGE, the Italian Society of Neurogastroenterology and Motility (SINGEM), and the Italian Society of Allergology, Asthma, and Clinical Immunology (SIAAIC). With regards to patients\' involvement, these guidelines involved the contribution of members of ESEO Italia, the Italian Association of Families Against EoE.
摘要：
嗜酸性粒细胞性食管炎（EoE）是一种慢性2型介导的食道炎性疾病，是最常见的嗜酸性粒细胞性胃肠道疾病。意大利EoE领域的专家(即，EoETALY共识组)，包括胃肠病学家，内窥镜医师,过敏/免疫学家，和儿科医生进行了Delphi程序，以制定针对EoE患者管理的最新共识声明，并根据最近的证据更新了意大利胃肠病学会（SIGE）的先前立场文件。使用公认的等级标准对建议证据的强度和质量进行分级。该准则分为两个文件：第一部分包括三章，即1)定义，流行病学,和发病机理；2）临床表现和自然史，3）诊断，第2部分包括两章：4）治疗和5）监测和随访。该文件已获得包括SIGE在内的三个意大利国家协会的认可，意大利神经胃肠病学和运动学会（SINGEM），和意大利变态反应学会,哮喘,和临床免疫学（SIAAIC）。关于患者的参与，这些指南涉及意大利ESEO成员的贡献，反对EoE的意大利家庭协会。
