RESULTS: The repeat-DCB group displayed significantly lower rates of 1-year primary patency and freedom from TLR compared to those of the de novo-DCB group (50.1% vs. 77.4%, p = 0.029 and 54.9% vs. 83.6%, p = 0.0.44, respectively). No significant differences were observed in early restenosis or MALE (10.7% vs. 5.9%, p = 0.455 and 48.3% vs. 73.4%, p = 0.055, respectively). Restenosis after DCB angioplasty was associated with repeat DCB (hazard ratio [HR], 5.13; 95% confidence interval [CI], 1.43-18.4; p = 0.012) and small vessel size of < 4.5 mm (HR, 6.25; 95% CI, 1.17-33.4; p = 0.032). Furthermore, restenosis after repeat DCB angioplasty was associated with the Peripheral Artery Calcification Scoring System (PACSS) grade 4 (HR, 4.20; 95% CI, 1.08-16.3; p = 0.038), small vessel size of < 4.5 mm (HR, 9.44; 95% CI, 1.21-73.7; p = 0.032), and intravascular ultrasound (IVUS) use (HR, 0.05; 95% CI, 0.01-0.44; p = 0.007).
CONCLUSIONS: The 1-year primary patency rate following repeat DCB angioplasty for femoropopliteal lesions was notably lower than that of DCB treatment for de novo lesions. Repeat DCB strategy was associated with an increased risk of patency loss. Regarding repeat restenosis after DCB treatments, PACSS grade 4 calcification and small vessel diameter of < 4.5 mm were associated with an increased risk of restenosis, whereas IVUS use correlated with a decreased risk of restenosis.
结果:与新生DCB组相比,重复DCB组的1年原发性通畅率和无TLR率显着降低(50.1%vs.77.4%,p=0.029和54.9%vs.83.6%,分别为p=0.0.44)。在早期再狭窄或男性中没有观察到显着差异(10.7%vs.5.9%,p=0.455和48.3%与73.4%,分别为p=0.055)。DCB血管成形术后再狭窄与重复DCB相关(风险比[HR],5.13;95%置信区间[CI],1.43-18.4;p=0.012)和<4.5mm的小血管尺寸(HR,6.25;95%CI,1.17-33.4;p=0.032)。此外,重复DCB血管成形术后的再狭窄与外周动脉钙化评分系统(PACSS)4级(HR,4.20;95%CI,1.08-16.3;p=0.038),小血管尺寸<4.5mm(HR,9.44;95%CI,1.21-73.7;p=0.032),和血管内超声(IVUS)的使用(HR,0.05;95%CI,0.01-0.44;p=0.007)。
结论:股——股———股————————————————————————————————————————————————————————————————————————————————重复DCB策略与通畅性丧失的风险增加相关。关于DCB治疗后的重复再狭窄,PACSS4级钙化和小血管直径<4.5mm与再狭窄风险增加相关。而IVUS使用与再狭窄风险降低相关。