PDF(Pubmed)
Abstract：
Kolmioviridae is a family for negative-sense RNA viruses with circular, viroid-like genomes of about 1.5-1.7 kb that are maintained in mammals, amphibians, birds, fish, insects and reptiles. Deltaviruses, for instance, can cause severe hepatitis in humans. Kolmiovirids encode delta antigen (DAg) and replicate using host-cell DNA-directed RNA polymerase II and ribozymes encoded in their genome and antigenome. They require evolutionary unrelated helper viruses to provide envelopes and incorporate helper virus proteins for infectious particle formation. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Kolmioviridae, which is available at ictv.global/report/kolmioviridae.
摘要：
Kolmioviridae是一个具有环状的负义RNA病毒家族，在哺乳动物中维持的类病毒基因组约1.5-1.7kb，两栖动物,鸟,鱼,昆虫和爬行动物。Deltavirus,例如,会导致人类严重的肝炎。Kolmiovirids编码δ抗原（DAg），并使用宿主细胞DNA指导的RNA聚合酶II和在其基因组和反基因组中编码的核酶进行复制。它们需要进化无关的辅助病毒来提供包膜并掺入辅助病毒蛋白以形成感染性颗粒。这是国际病毒分类学委员会（ICTV）关于Kolmioviridae家族的报告的摘要，可以在ictv上找到。全球/报告/kolmioviridae.
