PDF(Pubmed)
Abstract：
Millets are recognized for their health and nutritional values, and the United Nations declared 2023 the International Year of Millets. Among the several health and nutritional benefits of millets, their impact on hemoglobin concentration is important since anemia is a major public health issue in many countries. To investigate the effect of millet (including sorghum) consumption on hemoglobin concentration in the blood, a systematic review and meta-analysis were conducted. Thirteen published studies featuring randomized control trials involving 590 individuals in the intervention group and 549 control individuals were eligible for the meta-analysis. The difference-in-differences analysis revealed highly significant (p < 0.01) positive effects of millet consumption on hemoglobin concentration, with an effect size of +0.68 standardized mean difference units. The change in hemoglobin concentration observed in the intervention group was +13.6%, which is statistically significant (p < 0.0005), compared to that in the control group, which was +4.8% and not statistically significant (p = 0.1362). In four studies, the consumption of millets in the intervention group demonstrated a change from mild anemia to normal status among children, whereas there was no change in the control group. The findings provide evidence that the consumption of millets can improve blood hemoglobin concentration, likely resulting from increased iron intake. Further research is needed involving the assessment of iron content and bioavailability to better understand the effect variation among millet types and the mechanisms involved.
摘要：
小米因其健康和营养价值而受到认可，联合国宣布2023年为国际小米年。在小米的几种健康和营养益处中，它们对血红蛋白浓度的影响很重要，因为贫血是许多国家的主要公共卫生问题。探讨小米(含高粱)食用量对血液中血红蛋白浓度的影响,我们进行了系统评价和荟萃分析.13项发表的随机对照试验研究，涉及590名干预组个体和549名对照个体，符合荟萃分析的条件。差异分析显示小米消费对血红蛋白浓度的显著正效应(p<0.01),效应大小为+0.68个标准化平均差单位。干预组血红蛋白浓度变化+13.6%,具有统计学意义（p<0.0005），与对照组相比，+4.8%，无统计学意义(p=0.1362)。在四项研究中，干预组的小米消费表明儿童从轻度贫血转变为正常状态，而对照组没有变化。研究结果提供了证据，表明食用小米可以改善血液中的血红蛋白浓度，可能是铁摄入量增加所致。需要进行进一步的研究，包括评估铁含量和生物利用度，以更好地了解小米类型之间的影响变化及其相关机制。
