Abstract：
The use of atmospheric pressure chemical ionisation (APCI) compact mass spectrometry (CMS) was investigated for the analysis of jetsam and museum-archived ambergris and of ambergris components in perfumes. The data were compared with those from existing methods. Authentic samples of some individual ambergris constituents (ambrein, coprostanol, epicoprostanol and coprostanone), were also examined. Rapid APCI CMS was achieved using either a solids probe or a probe with solutions held in capillary melting point tubes. Interpretation is made of the spectra of the principal natural product components, the relative ion responses were measured and the elemental composition of key ions in the spectra confirmed using high resolution accurate mass APCI MS. Rapid analysis of ambergris by APCI CMS may prove to be a further convenient method of identifying ambrein, of measuring the relative ratios of ambrein and steroids in ambergris and even of quantifying the latter, with minimal sample preparation.
摘要：
研究了使用大气压化学电离（APCI）紧凑型质谱（CMS）来分析喷气式飞机和博物馆存档的龙舌兰酒以及香水中的龙舌兰酒成分。将数据与现有方法的数据进行比较。一些单独的龙涎香成分的真实样本(ambrein，去前列腺素,表前列腺素和共前列腺素)，也被检查过。使用固体探针或具有保持在毛细管熔点管中的溶液的探针实现快速APCICMS。对主要天然产物成分的光谱进行解释，测量了相对离子响应，并使用高分辨率精确质量APCIMS确认了光谱中关键离子的元素组成。通过APCICMS快速分析龙舌兰可能被证明是一种更方便的鉴定ambrein的方法，测量龙舌兰糖脂和类固醇的相对比例，甚至量化后者，用最少的样品制备。
