关键词: Vitamin D [25(OH)D)] acute respiratory tract infection human immunity retrovirus supplementation vitamin D deficiency

Mesh : Humans Female Young Adult Adult Vitamin D Vitamins / therapeutic use Vitamin D Deficiency / complications drug therapy Dietary Supplements Respiratory Tract Infections / diagnosis drug therapy etiology

来  源:   DOI:10.21873/invivo.13525   PDF(Pubmed)

Abstract:
BACKGROUND: Low serum concentrations of 25-hydroxyvitamin D correlate with higher susceptibility to acute respiratory tract infections (ARTIs). The case study presented here aims at sheding light on the correlation between vitamin D levels, the vitamin D supplement dose, and the incidence of ARTIs.
METHODS: A 23-year-old female patient with a vitamin D insufficiency was able to successfully increase her vitamin D levels from 45.60 nmol/l to 85.91 nmol/l (reference ranges 75-200 nmol/l) through the use of supplements. However, it was surprising to observe a decrease in vitamin D levels even though the patient continued taking supplements. Further examination indicated that the patient was experiencing common symptoms of an acute respiratory tract infection (ARTI). This case highlights the intricate connection between ARTIs and vitamin D intake.
CONCLUSIONS: This case study clearly demonstrates the intricate connection between vitamin D levels, supplement treatment, and ARTIs. The observed decrease in vitamin D levels during the course of supplementation, while the patient was suffering from an ARTI, suggests that respiratory infections may affect vitamin D metabolism.
摘要:
背景:25-羟基维生素D的低血清浓度与急性呼吸道感染(ARTI)的高易感性相关。这里提出的案例研究旨在揭示维生素D水平之间的相关性,补充维生素D的剂量,和ARTI的发病率。
方法:一名维生素D不足的23岁女性患者通过使用补充剂成功地将她的维生素D水平从45.60nmol/l提高到85.91nmol/l(参考范围75-200nmol/l)。然而,令人惊讶的是,即使患者继续服用补充剂,维生素D水平也会下降。进一步检查表明,患者正在经历急性呼吸道感染(ARTI)的常见症状。这个案例突出了ARTI和维生素D摄入之间的复杂联系。
结论:本案例研究清楚地表明了维生素D水平之间的复杂联系,补充治疗,和ARTIS。在补充过程中观察到的维生素D水平下降,当病人患有ARTI时,提示呼吸道感染可能会影响维生素D的代谢。
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