Abstract：
OBJECTIVE: The objective of the study was to describe the optical coherence tomographic features of a cat with acute corneal hydrops.
METHODS: A 4-year-old castrated male domestic shorthaired showing conjunctival redness, ocular discharge, and intermittent squinting of both eyes with asymmetrical disease onset.
METHODS: Complete ophthalmic examination and optical coherence tomography were performed.
RESULTS: On slit-lamp biomicroscopic examination, severe intrastromal fluid pockets with profound bullae were observed in the dorsomedial region in both eyes. A diagnosis of feline acute corneal hydrops was made in both eyes. Optical coherence tomography revealed profound stromal lamellar separation representing heterogeneous reflective areas, and fluid pockets and bullae of variable size were concomitant to Descemet\'s membrane detachment demonstrated by a well-defined homogeneous hyporeflective area. Upon reevaluation 30 days during healing process for both eyes, the thickened epithelia and the thinning pan-stromal areas were identified as homogeneously hyper-reflective epithelia and as heterogeneous hyper-reflectivity, respectively. A thickened posterior corneal surface was shown as heterogeneous with patchy hyper-reflectivity. Additionally, Descemet\'s membrane detachment in the initial presentation had two distinct forms suspicious of Descemet\'s membrane rupture in each eye: a break with rolled ends and a break with flat ends.
CONCLUSIONS: To the author\'s knowledge, this study represents the first documentation of in vivo detection of Descemet\'s membrane detachment and presumed rupture in a cat experiencing acute corneal hydrops. These observations strongly indicate that Descemet\'s membrane detachment/rupture acts as a most likely risk factor in the onset of acute corneal hydrops in cats.
METHODS: A 4-year-old castrated male domestic shorthaired showing conjunctival redness, ocular discharge, and intermittent squinting of both eyes with asymmetrical disease onset.
METHODS: Complete ophthalmic examination and optical coherence tomography were performed.
RESULTS: On slit-lamp biomicroscopic examination, severe intrastromal fluid pockets with profound bullae were observed in the dorsomedial region in both eyes. A diagnosis of feline acute corneal hydrops was made in both eyes. Optical coherence tomography revealed profound stromal lamellar separation representing heterogeneous reflective areas, and fluid pockets and bullae of variable size were concomitant to Descemet\'s membrane detachment demonstrated by a well-defined homogeneous hyporeflective area. Upon reevaluation 30 days during healing process for both eyes, the thickened epithelia and the thinning pan-stromal areas were identified as homogeneously hyper-reflective epithelia and as heterogeneous hyper-reflectivity, respectively. A thickened posterior corneal surface was shown as heterogeneous with patchy hyper-reflectivity. Additionally, Descemet\'s membrane detachment in the initial presentation had two distinct forms suspicious of Descemet\'s membrane rupture in each eye: a break with rolled ends and a break with flat ends.
CONCLUSIONS: To the author\'s knowledge, this study represents the first documentation of in vivo detection of Descemet\'s membrane detachment and presumed rupture in a cat experiencing acute corneal hydrops. These observations strongly indicate that Descemet\'s membrane detachment/rupture acts as a most likely risk factor in the onset of acute corneal hydrops in cats.
摘要：
目的：本研究的目的是描述患有急性角膜积水的猫的光学相干断层扫描特征。
方法：一名4岁阉割的男性家庭短肢显示结膜发红，眼放电,双眼间歇性斜视，不对称疾病发作。
方法：进行完整的眼科检查和光学相干断层扫描。
结果：关于裂隙灯生物显微镜检查，在双眼的背侧区域观察到严重的真皮内液囊和深大疱。双眼均诊断为猫急性角膜积液。光学相干断层扫描显示，代表异质反射区域的深层基质层状分离，以及可变大小的液袋和大泡伴随着Descemet的膜脱离，这由明确定义的均匀低反射区域证明。在双眼愈合过程中重新评估30天后，增厚的上皮和变薄的全基质区域被确定为均匀的高反射上皮和不均匀的高反射率，分别。增厚的后角膜表面显示为异质的，具有斑片状的高反射率。此外,在最初的表现中，Descemet的膜脱离有两种不同的形式，怀疑每只眼睛中的Descemet的膜破裂：末端卷曲的破裂和末端平坦的破裂。
结论：据作者所知，这项研究是首次在体内检测到急性角膜积液的猫中Descemet膜脱离和推测破裂的文献。这些观察结果强烈表明，Descemet的膜脱离/破裂是猫急性角膜积液发作的最可能的危险因素。
方法：一名4岁阉割的男性家庭短肢显示结膜发红，眼放电,双眼间歇性斜视，不对称疾病发作。
方法：进行完整的眼科检查和光学相干断层扫描。
结果：关于裂隙灯生物显微镜检查，在双眼的背侧区域观察到严重的真皮内液囊和深大疱。双眼均诊断为猫急性角膜积液。光学相干断层扫描显示，代表异质反射区域的深层基质层状分离，以及可变大小的液袋和大泡伴随着Descemet的膜脱离，这由明确定义的均匀低反射区域证明。在双眼愈合过程中重新评估30天后，增厚的上皮和变薄的全基质区域被确定为均匀的高反射上皮和不均匀的高反射率，分别。增厚的后角膜表面显示为异质的，具有斑片状的高反射率。此外,在最初的表现中，Descemet的膜脱离有两种不同的形式，怀疑每只眼睛中的Descemet的膜破裂：末端卷曲的破裂和末端平坦的破裂。
结论：据作者所知，这项研究是首次在体内检测到急性角膜积液的猫中Descemet膜脱离和推测破裂的文献。这些观察结果强烈表明，Descemet的膜脱离/破裂是猫急性角膜积液发作的最可能的危险因素。
