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Abstract：
OBJECTIVE: To explore the value of magnetic resonance imaging (MRI) and clinical features in identifying ovarian thecoma-fibroma (OTF) with cystic degeneration and ovary adenofibroma (OAF).
METHODS: A total of 40 patients with OTF (OTF group) and 28 patients with OAF (OAF group) were included in this retrospective study. Univariable and multivariable analyses were performed on clinical features and MRI between the two groups, and the receiver operating characteristic (ROC) curve was plotted to estimate the optimal threshold and predictive performance.
RESULTS: The OTF group had smaller cyst degeneration degree (P < .001), fewer black sponge sign (20% vs. 53.6%, P = .004), lower minimum apparent diffusion coefficient value (ADCmin) (0.986 (0.152) vs. 1.255 (0.370), P < .001), higher age (57.4 ± 14.2 vs. 44.1 ± 15.9, P = .001) and more postmenopausal women (72.5% vs. 28.6%, P < .001) than OAF. The area under the curve of MRI, clinical features and MRI combined with clinical features was 0.870, 0.841, and 0.954, respectively, and MRI combined with clinical features was significantly higher than the other two (P < .05).
CONCLUSIONS: The cyst degeneration degree, black sponge sign, ADCmin, age and menopause were independent factors in identifying OTF with cystic degeneration and OAF. The combination of MRI and clinical features has a good effect on the identification of the two.
CONCLUSIONS: This is the first time to distinguish OTF with cystic degeneration from OAF by combining MRI and clinical features. It shows the diagnostic performance of MRI, clinical features, and combination of the two. This will facilitate the discriminability and awareness of these two diseases among radiologists and gynaecologists.
METHODS: A total of 40 patients with OTF (OTF group) and 28 patients with OAF (OAF group) were included in this retrospective study. Univariable and multivariable analyses were performed on clinical features and MRI between the two groups, and the receiver operating characteristic (ROC) curve was plotted to estimate the optimal threshold and predictive performance.
RESULTS: The OTF group had smaller cyst degeneration degree (P < .001), fewer black sponge sign (20% vs. 53.6%, P = .004), lower minimum apparent diffusion coefficient value (ADCmin) (0.986 (0.152) vs. 1.255 (0.370), P < .001), higher age (57.4 ± 14.2 vs. 44.1 ± 15.9, P = .001) and more postmenopausal women (72.5% vs. 28.6%, P < .001) than OAF. The area under the curve of MRI, clinical features and MRI combined with clinical features was 0.870, 0.841, and 0.954, respectively, and MRI combined with clinical features was significantly higher than the other two (P < .05).
CONCLUSIONS: The cyst degeneration degree, black sponge sign, ADCmin, age and menopause were independent factors in identifying OTF with cystic degeneration and OAF. The combination of MRI and clinical features has a good effect on the identification of the two.
CONCLUSIONS: This is the first time to distinguish OTF with cystic degeneration from OAF by combining MRI and clinical features. It shows the diagnostic performance of MRI, clinical features, and combination of the two. This will facilitate the discriminability and awareness of these two diseases among radiologists and gynaecologists.
摘要：
目的：探讨磁共振成像（MRI）和临床特征在鉴别卵巢囊性变和腺纤维瘤（OAF）中的价值。
方法：纳入40例OTF患者（OTF组）和28例OAF患者（OAF组）。对两组的临床特征和MRI进行单变量和多变量分析，并绘制接收器工作特性（ROC）曲线以估计最佳阈值和预测性能。
结果：OTF组囊肿变性程度较小（p<0.001），更少的黑色海绵标志(20%与53.6%,p=0.004),下最小表观扩散系数值（ADCmin）（0.986（0.152）与1.255(0.370),p<0.001)，年龄较高（57.4±14.2vs.44.1±15.9，p=0.001）和更多的绝经后妇女（72.5％vs.28.6%,p<0.001)比OAF。MRI的AUC,临床特征和合并临床特征分别为0.870、0.841和0.954,而MRI联合临床特点明显高于其他两种(p<0.05)。
结论：囊肿变性程度，黑色海绵标志，ADCmin,年龄和绝经是确定OTF与囊性变性和OAF的独立因素。MRI与临床特点的联合对二者的辨认具有较好的后果。
结论：这是首次通过结合MRI和临床特征将OTF与囊性变性与OAF区分开。它显示了MRI的诊断性能，临床特征,以及两者的结合。这将有助于放射科医生和妇科医生对这两种疾病的辨别性和认识。
方法：纳入40例OTF患者（OTF组）和28例OAF患者（OAF组）。对两组的临床特征和MRI进行单变量和多变量分析，并绘制接收器工作特性（ROC）曲线以估计最佳阈值和预测性能。
结果：OTF组囊肿变性程度较小（p<0.001），更少的黑色海绵标志(20%与53.6%,p=0.004),下最小表观扩散系数值（ADCmin）（0.986（0.152）与1.255(0.370),p<0.001)，年龄较高（57.4±14.2vs.44.1±15.9，p=0.001）和更多的绝经后妇女（72.5％vs.28.6%,p<0.001)比OAF。MRI的AUC,临床特征和合并临床特征分别为0.870、0.841和0.954,而MRI联合临床特点明显高于其他两种(p<0.05)。
结论：囊肿变性程度，黑色海绵标志，ADCmin,年龄和绝经是确定OTF与囊性变性和OAF的独立因素。MRI与临床特点的联合对二者的辨认具有较好的后果。
结论：这是首次通过结合MRI和临床特征将OTF与囊性变性与OAF区分开。它显示了MRI的诊断性能，临床特征,以及两者的结合。这将有助于放射科医生和妇科医生对这两种疾病的辨别性和认识。
