PDF(Pubmed)
Abstract：
Background and Objectives: Mild cognitive impairment (MCI) is an early stage of dementia in which everyday tasks can be maintained; however, notable challenges may occur in memory, focus, and problem-solving skills. Therefore, motor-cognitive dual-task training is warranted to prevent cognitive decline and improve cognition in aging populations. This study aimed to determine the influence of such dual-task activities during straight and curved walking on the activities of the prefrontal cortex and associated gait variables in older adults with MCI. Materials and Methods: Twenty-seven older adults aged ≥65 years and identified as having MCI based on their scores (18-23) on the Korean Mini-Mental State Examination were enrolled. The participants performed four task scenarios in random order: walking straight, walking straight with a cognitive task, walking curved, and walking curved with a cognitive task. The activation of the prefrontal cortex, which is manifested by a change in the level of oxyhemoglobin, was measured using functional near-infrared spectroscopy. The gait speed and step count were recorded during the task performance. Results: Significant differences were observed in prefrontal cortex activation and gait variables (p < 0.05). Specifically, a substantial increase was observed in prefrontal cortex activation during a dual task compared with that during a resting-state (p < 0.013). Additionally, significant variations were noted in the gait speed and step count (p < 0.05). Conclusions: This study directly demonstrates the impact of motor-cognitive dual-task training on prefrontal cortex activation in older adults with MCI, suggesting the importance of including such interventions in enhancing cognitive function.
摘要：
背景与目的:轻度认知障碍(MCI)是痴呆的早期阶段,在该阶段中日常任务可以维持,值得注意的挑战可能发生在记忆中，焦点,和解决问题的能力。因此,运动-认知双重任务训练是必要的，以防止认知能力下降和提高认知在老年人群。这项研究旨在确定直线和弯曲行走过程中这种双重任务活动对MCI老年人前额叶皮层活动和相关步态变量的影响。材料和方法：招募了27名年龄≥65岁的老年人，根据他们在韩国简易精神状态检查中的得分（18-23）确定患有MCI。参与者以随机顺序执行了四个任务场景：直走，带着认知任务直走，弯弯的走路，带着认知任务弯腰走路。前额叶皮层的激活,这表现为氧合血红蛋白水平的变化，使用功能近红外光谱进行测量。在任务执行期间记录步态速度和步数。结果：前额叶皮层激活和步态变量存在显著差异（p<0.05）。具体来说,与静息状态相比,双重任务期间前额叶皮层激活显著增加(p<0.013).此外,步态速度和步数存在显著差异(p<0.05).结论：这项研究直接证明了运动-认知双重任务训练对MCI老年人前额叶皮层激活的影响，表明包括此类干预措施对增强认知功能的重要性。
