关键词: May–Thurner syndrome case series childhood hereditary iliac compression syndrome pulmonary embolism

来  源:   DOI:10.3390/life14020221   PDF(Pubmed)

Abstract:
May-Thurner syndrome is a venous compression syndrome of the pelvic vessels that represents a relevant risk factor for thrombus formation. The standard procedure to secure a diagnosis is venography, followed by endovascular therapy as the preferred treatment choice if the patient is symptomatic. In our case series, there are three related patients with May-Thurner syndrome. A 16-year-old female was admitted with pulmonary embolism, dyspnoea and hip pain. The compression syndrome was diagnosed with interventional venography, and the patient received venous stent implantation. Due to her family history, we also suspected her mother to be affected by the syndrome and elucidated the diagnosis shortly afterwards by invasive venography. Subsequently, we examined the patient\'s 19-year-old brother, and magnetic resonance imaging confirmed May-Thurner syndrome. A similar case series has not been published before. In this case, the family relation indicates a possible hereditary aspect of May-Thurner syndrome. This hypothesis should be the subject of further research. In conclusion, it is essential to assess family history thoroughly when treating patients with May-Thurner syndrome.
摘要:
May-Thurner综合征是盆腔血管的静脉压迫综合征,是血栓形成的相关危险因素。确保诊断的标准程序是静脉造影,如果患者有症状,则血管内治疗是首选治疗选择。在我们的案例系列中,有3名患者患有May-Thurner综合征。一名十六岁女性因肺栓塞入院,呼吸困难和髋部疼痛。介入性静脉造影诊断为压迫综合征,患者接受静脉支架植入术。由于她的家族史,我们还怀疑她的母亲受到该综合征的影响,并在随后不久通过侵入性静脉造影阐明了诊断。随后,我们检查了病人19岁的弟弟,磁共振成像证实了May-Thurner综合征。类似的案例系列以前尚未发布。在这种情况下,家庭关系表明可能是May-Thurner综合征的遗传方面。这一假设应该是进一步研究的主题。总之,在治疗May-Thurner综合征患者时,彻底评估家族史至关重要.
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