关键词: herpes simplex immunosuppression virus latency

来  源:   DOI:10.21142/2523-2754-1001-2022-099   PDF(Pubmed)

Abstract:
Herpes simplex virus, after the first infection, can remain dormant in the lymph nodes and reactivate at any time due to certain factors and/or stimuli causing effects in the patient. The purpose of this literature review is to update scientific information on the factors that predispose to the reactivation of herpes simplex virus. A comprehensive literature review was conducted in the LILACS, SciELO, PubMed, Scopus and the following keywords were used: herpes simplex, reactivation, latency and risks. A factor is reactivation by immunosuppression due to the intake of immunosuppressants or oncological therapy. Another factor is psychological stress, in which the hormones released act on mediating signs of reactivation. Sun exposure that reactivates the virus in infected neurons and infection in pregnant women can trigger complications in the fetus and delivery.
摘要:
单纯疱疹病毒,第一次感染后,可以在淋巴结中保持休眠状态,并且由于某些因素和/或刺激引起患者的影响而在任何时候重新激活。本文献综述的目的是更新有关导致单纯疱疹病毒再激活的因素的科学信息。在LILACS中进行了全面的文献综述,SciELO,PubMed,使用Scopus和以下关键词:单纯疱疹,重新激活,延迟和风险。一个因素是由于摄入免疫抑制剂或肿瘤治疗而通过免疫抑制重新激活。另一个因素是心理压力,其中释放的激素作用于介导重新激活的迹象。阳光照射会重新激活受感染神经元中的病毒和孕妇的感染,从而引发胎儿和分娩并发症。
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