PDF(Pubmed)
Abstract：
UNASSIGNED: Psychoeducational interventions (PEIs), which provide both information and emotional and psychosocial support, may address the unmet needs of the caregivers of adolescent and young adult patients with cancer.
UNASSIGNED: To explore the effects of an instant messaging-delivered PEI on anxiety, depression, quality of life (QOL), and coping and determine whether the intervention reduces caregivers\' unmet needs.
UNASSIGNED: This randomized clinical trial using an intention-to-treat protocol was conducted from April 1 to September 14, 2022, in a tertiary cancer hospital in China and included caregivers of patients diagnosed with cancer at age 15 to 39 years recruited using convenience sampling.
UNASSIGNED: Caregivers were allocated 1:1 using a randomized block scheme to the intervention or control group. The intervention group received a 5-week PEI and usual care, whereas the control group received only usual care. The PEI was delivered through articles and calls through an instant messaging application.
UNASSIGNED: The primary outcomes were changes in the levels of caregivers\' anxiety and depression, measured using the 7-Item Generalized Anxiety Disorder Scale and the Patient Health Questionnaire 9, respectively. The secondary outcomes were changes in the levels of caregivers\' QOL, coping, and unmet needs.
UNASSIGNED: Of the 160 participants, 92 (57.5%) were male; mean (SD) age was 40.27 (8.33) years. Compared with the control group, the intervention group had significantly greater reduction in severity of anxiety (B = -3.231; 95% CI, -4.746 to -1.716; P < .001) and depression (B = -3.253; 95% CI, -5.052 to -1.454; P < .001), smaller reduction in QOL (B = 13.574; 95% CI, 0.488-26.661; P = .04), and greater reduction in unmet needs (B = -12.136; 95% CI, -18.307 to -5.965; P < .001) after the intervention. Twelve weeks after baseline, the intervention group demonstrated a significantly greater reduction only in severity of anxiety (B = -1.890; 95% CI, -3.382 to -0.397; P = .01).
UNASSIGNED: In this randomized clinical trial of a mobile instant messaging-delivered PEI, caregivers\' unmet needs, anxiety, and depression decreased significantly and QOL declined at a significantly slower rate immediately after the intervention in the intervention group compared with the control group. A sustained effect on anxiety was observed 12 weeks after baseline.
UNASSIGNED: Chinese Clinical Trial Registry identifier: ChiCTR2200055951.
UNASSIGNED: To explore the effects of an instant messaging-delivered PEI on anxiety, depression, quality of life (QOL), and coping and determine whether the intervention reduces caregivers\' unmet needs.
UNASSIGNED: This randomized clinical trial using an intention-to-treat protocol was conducted from April 1 to September 14, 2022, in a tertiary cancer hospital in China and included caregivers of patients diagnosed with cancer at age 15 to 39 years recruited using convenience sampling.
UNASSIGNED: Caregivers were allocated 1:1 using a randomized block scheme to the intervention or control group. The intervention group received a 5-week PEI and usual care, whereas the control group received only usual care. The PEI was delivered through articles and calls through an instant messaging application.
UNASSIGNED: The primary outcomes were changes in the levels of caregivers\' anxiety and depression, measured using the 7-Item Generalized Anxiety Disorder Scale and the Patient Health Questionnaire 9, respectively. The secondary outcomes were changes in the levels of caregivers\' QOL, coping, and unmet needs.
UNASSIGNED: Of the 160 participants, 92 (57.5%) were male; mean (SD) age was 40.27 (8.33) years. Compared with the control group, the intervention group had significantly greater reduction in severity of anxiety (B = -3.231; 95% CI, -4.746 to -1.716; P < .001) and depression (B = -3.253; 95% CI, -5.052 to -1.454; P < .001), smaller reduction in QOL (B = 13.574; 95% CI, 0.488-26.661; P = .04), and greater reduction in unmet needs (B = -12.136; 95% CI, -18.307 to -5.965; P < .001) after the intervention. Twelve weeks after baseline, the intervention group demonstrated a significantly greater reduction only in severity of anxiety (B = -1.890; 95% CI, -3.382 to -0.397; P = .01).
UNASSIGNED: In this randomized clinical trial of a mobile instant messaging-delivered PEI, caregivers\' unmet needs, anxiety, and depression decreased significantly and QOL declined at a significantly slower rate immediately after the intervention in the intervention group compared with the control group. A sustained effect on anxiety was observed 12 weeks after baseline.
UNASSIGNED: Chinese Clinical Trial Registry identifier: ChiCTR2200055951.
摘要：
■心理教育干预（PEIs），提供信息、情感和社会心理支持，可以解决青少年和年轻成年癌症患者的护理人员未满足的需求。
■为了探索即时消息传递的PEI对焦虑的影响，抑郁症,生活质量（QOL），并应对并确定干预措施是否减少了护理人员未满足的需求。
■这项使用意向治疗方案的随机临床试验于2022年4月1日至9月14日在中国一家三级癌症医院进行，包括使用便利抽样招募的15至39岁被诊断患有癌症的患者的护理人员。
■使用随机区组方案将照顾者1:1分配给干预组或对照组。干预组接受为期5周的PEI和常规护理，而对照组仅接受常规护理。PEI是通过即时消息应用程序通过文章和调用传递的。
■主要结果是护理人员焦虑和抑郁水平的变化，分别使用7项广义焦虑症量表和患者健康问卷9进行测量。次要结果是护理人员生活水平的变化，应对,和未满足的需求。
■在160名参与者中，92（57.5％）为男性；平均（SD）年龄为40.27（8.33）岁。与对照组相比,干预组的焦虑严重程度（B=-3.231;95％CI，-4.746至-1.716;P<.001）和抑郁严重程度（B=-3.253;95％CI，-5.052至-1.454;P<.001）显着降低，生活质量下降幅度较小(B=13.574；95%CI，0.488-26.661；P=.04)，干预后，未满足的需求减少幅度更大（B=-12.136；95％CI，-18.307至-5.965；P<.001）。基线后12周，干预组仅在焦虑严重程度方面表现出显著更大的降低(B=-1.890;95%CI,-3.382~-0.397;P=0.01).
■在这项由移动即时消息传递的PEI的随机临床试验中，护理人员未满足的需求，焦虑,与对照组相比，干预组干预后立即抑郁显著下降，生活质量下降速度显著减慢。基线后12周观察到对焦虑的持续影响。
■中国临床试验注册中心标识符：ChiCTR2200055951。
■为了探索即时消息传递的PEI对焦虑的影响，抑郁症,生活质量（QOL），并应对并确定干预措施是否减少了护理人员未满足的需求。
■这项使用意向治疗方案的随机临床试验于2022年4月1日至9月14日在中国一家三级癌症医院进行，包括使用便利抽样招募的15至39岁被诊断患有癌症的患者的护理人员。
■使用随机区组方案将照顾者1:1分配给干预组或对照组。干预组接受为期5周的PEI和常规护理，而对照组仅接受常规护理。PEI是通过即时消息应用程序通过文章和调用传递的。
■主要结果是护理人员焦虑和抑郁水平的变化，分别使用7项广义焦虑症量表和患者健康问卷9进行测量。次要结果是护理人员生活水平的变化，应对,和未满足的需求。
■在160名参与者中，92（57.5％）为男性；平均（SD）年龄为40.27（8.33）岁。与对照组相比,干预组的焦虑严重程度（B=-3.231;95％CI，-4.746至-1.716;P<.001）和抑郁严重程度（B=-3.253;95％CI，-5.052至-1.454;P<.001）显着降低，生活质量下降幅度较小(B=13.574；95%CI，0.488-26.661；P=.04)，干预后，未满足的需求减少幅度更大（B=-12.136；95％CI，-18.307至-5.965；P<.001）。基线后12周，干预组仅在焦虑严重程度方面表现出显著更大的降低(B=-1.890;95%CI,-3.382~-0.397;P=0.01).
■在这项由移动即时消息传递的PEI的随机临床试验中，护理人员未满足的需求，焦虑,与对照组相比，干预组干预后立即抑郁显著下降，生活质量下降速度显著减慢。基线后12周观察到对焦虑的持续影响。
■中国临床试验注册中心标识符：ChiCTR2200055951。
