PDF(Pubmed)
Abstract：
Organophosphate insecticide spray poses potential threat of contamination of environmental components their accumulation in aquatic organisms. Although various physiological deficits associated with their exposure in fishes are documented, yet their retention in their edible muscle tissues has been poorly studied. In this context, the study was undertaken to ascertain the bioaccumulation of two organophosphate insecticide compounds (dimethoate and chlorpyrifos) in the muscles of juvenile Cyprinus carpio. The study could provide insight into the risks to human health associated with consuming contaminated fish flesh. The fishes exposed to various concentrations of dimethoate and chlorpyrifos in-vivo for 96 to ascertain the uptake and retention of these insecticides in the muscle. Results indicated that fish muscles accumulated the residues at all the concentrations with the recovery of 2.99% (0.032 ppm) of dimethoate exposed to LC50 concentrations. In contrast, the chlorpyrifos residues were found Below the Detection Level (BDL) in the fishes exposed to LC50 concentrations. The percentage bioaccumulation of dimethoate in fish muscle was 88.10%, and that of chlorpyrifos was BDL. The bio-concentration factor was dose-dependent and increased with increasing doses of both insecticides. The study invites attention to human health risk assessment in the regions where contaminated fish are consumed without scientific supervision.
摘要：
有机磷杀虫剂喷雾对其在水生生物中积累的环境成分造成污染的潜在威胁。尽管记录了与鱼类接触相关的各种生理缺陷，然而，它们在可食用肌肉组织中的保留一直缺乏研究。在这种情况下，进行这项研究是为了确定两种有机磷酸盐杀虫剂化合物（乐果和毒死rif）在幼年鲤鱼肌肉中的生物积累。该研究可以深入了解食用受污染的鱼肉对人类健康的风险。鱼在体内暴露于各种浓度的乐果和毒死rif96，以确定这些杀虫剂在肌肉中的吸收和保留。结果表明，鱼的肌肉在所有浓度下都会积累残留物，而暴露于LC50浓度的乐果回收率为2.99％（0.032ppm）。相比之下,在暴露于LC50浓度的鱼类中，发现毒死蜱的残留物低于检测水平（BDL）。乐果在鱼肌肉中的生物累积率为88.10%，毒死蜱是BDL。生物浓度因子是剂量依赖性的，并且随着两种杀虫剂剂量的增加而增加。该研究提请注意在没有科学监督的情况下食用受污染鱼类的地区的人类健康风险评估。
