Abstract：
OBJECTIVE: To evaluate the safety, efficacy and postoperative visual quality of small incision lenticule extraction (SMILE) and Wavefront-Guided Laser in situ keratomileusis (WFG-LASIK) and to analyze their efficacy in correcting astigmatism.
METHODS: A systematic literature search was performed using Cochrane Collaboration methodology. Databases searched included PubMed, Embase, the Cochrane Library and Web of Science. RevMan software version 5.3.0 was used for meta-analysis.
RESULTS: A total of 976 eyes were included in 8 studies, of which 539 eyes underwent SMILE and 437 eyes underwent WFG-LASIK. There were no statistically significant differences in the proportion of eyes achieving uncorrected distance visual acuity of 20/20 or better (P=0.18), the proportion of eyes within±0.50 diopter of target refraction postoperatively (P=0.10), or the postoperative magnitude of cylinder (P=0.10). Regarding the Alpins vector analysis of astigmatism, there was no statistically significant difference in the surgical magnitude of error (P=0.09) between the two groups. WFG-LASIK has a lower surgical angle of error (P= 0.002) and higher surgical correction index of cylinder (P=0.03) than SMILE. In terms of aberrations, higher order aberrations (P=0.46), spherical aberrations (P=0.22) and trefoil (P=0.56) were not statistically different, while WFG-LASIK induced less coma than SMILE surgery (P=0.02).
CONCLUSIONS: Both SMILE and WFG-LASIK are safe and effective ways to correct myopia and astigmatism. Compared with SMILE, WFG-LASIK has a lower surgical angle of error, higher surgical correction index of cylinder and induces less coma.
METHODS: A systematic literature search was performed using Cochrane Collaboration methodology. Databases searched included PubMed, Embase, the Cochrane Library and Web of Science. RevMan software version 5.3.0 was used for meta-analysis.
RESULTS: A total of 976 eyes were included in 8 studies, of which 539 eyes underwent SMILE and 437 eyes underwent WFG-LASIK. There were no statistically significant differences in the proportion of eyes achieving uncorrected distance visual acuity of 20/20 or better (P=0.18), the proportion of eyes within±0.50 diopter of target refraction postoperatively (P=0.10), or the postoperative magnitude of cylinder (P=0.10). Regarding the Alpins vector analysis of astigmatism, there was no statistically significant difference in the surgical magnitude of error (P=0.09) between the two groups. WFG-LASIK has a lower surgical angle of error (P= 0.002) and higher surgical correction index of cylinder (P=0.03) than SMILE. In terms of aberrations, higher order aberrations (P=0.46), spherical aberrations (P=0.22) and trefoil (P=0.56) were not statistically different, while WFG-LASIK induced less coma than SMILE surgery (P=0.02).
CONCLUSIONS: Both SMILE and WFG-LASIK are safe and effective ways to correct myopia and astigmatism. Compared with SMILE, WFG-LASIK has a lower surgical angle of error, higher surgical correction index of cylinder and induces less coma.
摘要：
目的：为了评估安全性，小切口微透镜取出术（SMILE）和波前引导激光原位角膜磨镶术（WFG-LASIK）的疗效和术后视觉质量，并分析其矫正散光的疗效。
方法：使用CochraneCollaboration方法进行了系统的文献检索。搜索的数据库包括PubMed,Embase,Cochrane图书馆和WebofScience.使用RevMan软件5.3.0版进行荟萃分析。
结果：共976只眼纳入了8项研究，其中539眼接受了SMILE，437眼接受了WFG-LASIK。未矫正视力达到20/20或更高的眼比例差异无统计学意义(P=0.18)。术后目标屈光度±0.50屈光度范围内的眼睛比例（P=0.10），或术后圆柱大小（P=0.10）。关于散光的Alpins向量分析，两组间手术误差幅度无统计学差异(P=0.09).与SMILE相比，WFG-LASIK具有更低的手术误差角度（P=0.002）和更高的手术矫正指数（P=0.03）。在像差方面，高阶像差(P=0.46)，球差(P=0.22)和三叶形(P=0.56)无统计学差异,而WFG-LASIK诱导的昏迷低于SMILE手术(P=0.02)。
结论：SMILE和WFG-LASIK都是矫正近视和散光的安全有效方法。与微笑相比，WFG-LASIK具有较低的手术误差角度，较高的圆筒手术矫正指数，诱发昏迷较少。
方法：使用CochraneCollaboration方法进行了系统的文献检索。搜索的数据库包括PubMed,Embase,Cochrane图书馆和WebofScience.使用RevMan软件5.3.0版进行荟萃分析。
结果：共976只眼纳入了8项研究，其中539眼接受了SMILE，437眼接受了WFG-LASIK。未矫正视力达到20/20或更高的眼比例差异无统计学意义(P=0.18)。术后目标屈光度±0.50屈光度范围内的眼睛比例（P=0.10），或术后圆柱大小（P=0.10）。关于散光的Alpins向量分析，两组间手术误差幅度无统计学差异(P=0.09).与SMILE相比，WFG-LASIK具有更低的手术误差角度（P=0.002）和更高的手术矫正指数（P=0.03）。在像差方面，高阶像差(P=0.46)，球差(P=0.22)和三叶形(P=0.56)无统计学差异,而WFG-LASIK诱导的昏迷低于SMILE手术(P=0.02)。
结论：SMILE和WFG-LASIK都是矫正近视和散光的安全有效方法。与微笑相比，WFG-LASIK具有较低的手术误差角度，较高的圆筒手术矫正指数，诱发昏迷较少。
