Abstract：
We evaluated changes in hyperhydration and beverage hydration index (BHI, a composite measure of fluid balance after consuming a test beverage relative to water) during resting, induced by the consumption of beverages containing glycerol and sodium supplemented with fast-absorbing sucrose or slow-absorbing isomaltulose. In a randomized crossover, single-blinded protocol (clinical trials registry: UMIN000042644), 14 young physically active adults (three women) consumed 1 L of beverage containing either 7% glycerol + 0.5% sodium (Gly + Na), Gly + Na plus 7% sucrose (Gly + Na + Suc), Gly + Na plus 7% isomaltulose (Gly + Na + Iso), or water (CON) over a 40 min period. We assessed the change in plasma volume (ΔPV), BHI (calculated from cumulative urine output following consumption of water relative to that of the beverage), and blood glucose and sodium for 180 min after initiating ingestion. Total urine volume was reduced in all beverages containing glycerol and sodium compared to CON (all P ≤ 0.002). The addition of isomaltulose increased BHI by ∼45% (3.43 ± 1.0 vs. 2.50 ± 0.7 for Gly + Na, P = 0.011) whereas sucrose did not (2.6 ± 0.6, P = 0.826). The PV expansion was earliest for Gly + Na (30 min), slower for Gly + Na + Suc (90 min), and slowest for Gly + Na + Iso (120 min) with a concomitant lag in the increase of blood glucose and sodium concentrations. Supplementation of beverages containing glycerol and sodium with isomaltulose but not sucrose enhances BHI from those of glycerol and sodium only under a resting state, likely due to the slow absorption of isomaltulose-derived monosaccharides (i.e., glucose and fructose).
摘要：
我们评估了水合过多和饮料水合指数的变化(BHI，在休息期间消耗测试饮料相对于水的液体平衡的复合量度)，由消耗含有甘油和钠的饮料以及快速吸收的蔗糖或慢吸收的异麦芽酮糖引起。在随机交叉中，单盲方案（临床试验注册：UMIN000042644），14名年轻的运动成年人（3名女性）消耗了1升含有7％甘油+0.5％钠（Gly+Na）的饮料，Gly+Na加7%蔗糖(Gly+Na+Suc),Gly+Na+7%异麦芽酮糖(Gly+Na+Iso),或水（CON）超过40分钟。我们评估了血浆体积（ΔPV）的变化，BHI（根据相对于饮料的水消耗后的累积尿量计算），开始摄入后180分钟，血糖和钠。与CON相比，所有含甘油和钠的饮料的总尿量均减少（均P<0.002）。异麦芽酮糖的添加使BHI增加~45%(Gly+Na为3.43±1.0vs2.50±0.7,P=0.011），而蔗糖则没有（2.6±0.6，P=0.826）。PV膨胀最早是Gly+Na(30分钟)，Gly+Na+Suc较慢(90分钟),对于GlyNaIso（120分钟）最慢，伴随着血糖和钠浓度增加的滞后。补充含有甘油和钠的饮料与异麦芽酮糖而不是蔗糖仅在静息状态下增强BHI从甘油和钠的那些，可能是由于异麦芽酮糖衍生的单糖吸收缓慢(即，葡萄糖和果糖)。
