Abstract:
UNASSIGNED: Bizarre parosteal osteochondromatous proliferation (BPOP) is also known as Nora\'s disease. It is a benign lesion. Even though recent studies showed probable neoplastic etiology, the exact cause is unknown. BPOP commonly involves small bones of hands and feet. This condition is rare and very few cases are reported. In this report, two cases are presented with clinical, radiological, and histopathological findings. The first case was a 38-year-old female presented with 3-year history of mild painful swelling in the left middle finger and the second case was a 28-year-old male with the left leg swelling for 8 years. On radiology, both cases showed surface lesion with uninvolved medullary cavity. Excision specimen of both the lesions subjected for histopathological examination. Microscopically, there was irregular maturation of the bone and cartilage. Cartilage showed purplish-blue color (blue bone) with bizarre chondrocytes. BPOP is a rare benign condition. Awareness of clinical radiological and microscopic findings is needed for correct diagnosis and to differentiate it from other mimicking benign and malignant conditions.
摘要:
■奇怪的骨旁骨软骨瘤增生(BPOP)也被称为诺拉病。这是良性病变。尽管最近的研究表明可能的肿瘤病因,确切原因不明。BPOP通常涉及手和脚的小骨头。这种情况很少见,报告的病例很少。在这份报告中,两例病例表现为临床,放射学,和组织病理学发现。第一例是一名38岁的女性,有3年的左中指轻度疼痛肿胀史,第二例是一名28岁的男性,左腿肿胀8年。在放射学上,两例均为表面病变,髓腔未受累。切除两个病变的标本进行组织病理学检查。微观上,骨骼和软骨不规则成熟。软骨显示紫蓝色(蓝骨),具有奇异的软骨细胞。BPOP是一种罕见的良性疾病。需要了解临床放射学和微观发现,才能正确诊断并将其与其他模拟的良性和恶性状况区分开。