We enrolled 85 patients with varying degrees of pelvic floor dysfunction (PFD) and 85 age- and gender-matched controls in this retrospective study. All patients had MR defecography images, while all controls had pelvic MR images obtained for other reasons. Group comparisons were performed using independent samples t-tests and Mann-Whitney U tests. The receiver operating curve (ROC) was constructed to establish a cut-off value for a normal LAM volume. Interrater reliability was assessed by calculating the intraclass correlation coefficient. A P value of less than 0.05 was considered statistically significant.
Volumetric measurements revealed that the control group had higher LAM volumes, and the ROC curve analysis indicated a cut-off value of 38934.3 mm3 with a sensitivity of 0.812 and specificity of 0.8 for PFD assessment using LAM volumetric measurement. Gender did not significantly affect LAM volume in the control group.
Alongside the useful structural and functional information acquired from MR defecography images, volumetric analysis, and three-dimensional reconstructions of LAM may help to improve the accuracy of the diagnosis.
方法:在这项回顾性研究中,我们招募了85例不同程度的盆底功能障碍(PFD)患者和85例年龄和性别匹配的对照。所有患者均有MR排粪造影图像,而所有对照均因其他原因获得盆腔MR图像。使用独立样本t检验和Mann-WhitneyU检验进行组比较。构建受试者工作曲线(ROC)以建立正常LAM体积的截止值。通过计算组内相关系数来评估评分者间的可靠性。小于0.05的P值被认为具有统计学意义。
结果:体积测量显示对照组的LAM体积更高,ROC曲线分析表明,使用LAM体积测量进行PFD评估的截断值为38934.3mm3,灵敏度为0.812,特异性为0.8。性别对对照组的LAM体积没有显着影响。
结论:除了从MR排粪造影图像获得的有用的结构和功能信息,体积分析,LAM的三维重建可能有助于提高诊断的准确性。