PDF(Pubmed)
Abstract：
An early-adolescent boy with a background of Pitt-Hopkins syndrome was transferred to a tertiary paediatric hospital with symptoms of a functional large bowel obstruction. He required extensive surgical intervention including a transverse colectomy, drainage of an abdominal abscess, laparotomy and adhesionolysis, and insertion of a gastrostomy and jejunostomy. He had significant ongoing issues with visceral hyperalgesia that was refractory to a wide range of pharmacological treatments and required admission to the intensive care unit on multiple occasions, and consultations with international experts in Pitt-Hopkins syndrome and pain specialists. An individualised pain plan was created and adjusted over time, with eventual good effect, and he was transferred back to his regional hospital and subsequently discharged home.
摘要：
一名患有皮特-霍普金斯综合征的青春期男孩被转移到三级儿科医院，症状为功能性大肠梗阻。他需要广泛的手术干预，包括横结肠切除术，腹腔脓肿引流,剖腹手术和粘连松解术，插入胃造口术和空肠造口术。他患有内脏痛觉过敏的严重问题，这种问题对各种药物治疗都很难处理，需要多次进入重症监护病房，并与皮特-霍普金斯综合症和疼痛专家的国际专家进行磋商。制定了个性化的疼痛计划，并随着时间的推移进行了调整，最终效果良好，他被转移回他的地区医院，随后出院回家。
