{Reference Type}: Case Reports
{Title}: Complex visceral hyperalgesia in an adolescent with Pitt-Hopkins syndrome.
{Author}: Reaney L;Collins A;
{Journal}: BMJ Case Rep
{Volume}: 17
{Issue}: 2
{Year}: 2024 Feb 19
暂无{DOI}: 10.1136/bcr-2023-258257
{Abstract}: An early-adolescent boy with a background of Pitt-Hopkins syndrome was transferred to a tertiary paediatric hospital with symptoms of a functional large bowel obstruction. He required extensive surgical intervention including a transverse colectomy, drainage of an abdominal abscess, laparotomy and adhesionolysis, and insertion of a gastrostomy and jejunostomy. He had significant ongoing issues with visceral hyperalgesia that was refractory to a wide range of pharmacological treatments and required admission to the intensive care unit on multiple occasions, and consultations with international experts in Pitt-Hopkins syndrome and pain specialists. An individualised pain plan was created and adjusted over time, with eventual good effect, and he was transferred back to his regional hospital and subsequently discharged home.