PDF(Pubmed)
Abstract：
Cardiovascular diseases (CVD), type 2 diabetes (T2D), and cancer are a significant public health burden in the Nordic and Baltic countries. High intake of eggs, mainly due to its high cholesterol content, has been suggested to have adverse health effects. The purpose of this scoping review is to describe the evidence related to the impact of egg intake on health. A literature search identified 38 systematic reviews and meta-analyses on egg consumption in relation to health outcomes published between 2011 and 30 April 2022. Overall, current evidence from systematic reviews of randomized clinical trials indicates that higher egg intake may increase serum total cholesterol concentration and the ratio of low-density lipoprotein to high-density lipoprotein cholesterol, but with substantial heterogeneity in the response. However, recent evidence from observational studies does not provide strong support for a detrimental role of moderate egg consumption (up to one egg/day) on the risk of CVD, especially in the European studies. The overall evidence from observational studies indicates that egg consumption is not associated with increased risk of mortality or T2D in European study populations. There is also little support for a role of egg consumption in cancer development, although a weak association with higher risk of certain cancers has been found in some studies, mainly case-control studies. Again, no associations with cancer risk have been observed in European studies. Systematic reviews and meta-analyses of egg consumption in relation to other health-related outcomes are scarce. There are also limited data available on the associations between the consumption of more than one egg/day and risk of diseases. Based on the available evidence, one egg/day is unlikely to adversely affect overall disease risk.
摘要：
心血管疾病（CVD），2型糖尿病（T2D），癌症是北欧和波罗的海国家的重大公共卫生负担。鸡蛋摄入量高，主要是因为它的胆固醇含量高,有人建议对健康有不良影响。这项范围审查的目的是描述与鸡蛋摄入对健康影响有关的证据。文献检索确定了2011年至2022年4月30日发表的关于鸡蛋消费与健康结果相关的38项系统评价和荟萃分析。总的来说,随机临床试验系统评价的最新证据表明，较高的鸡蛋摄入量可能会增加血清总胆固醇浓度和低密度脂蛋白与高密度脂蛋白胆固醇的比例，但反应有很大的异质性。然而,观察性研究的最新证据并未为适度食用鸡蛋（每天最多食用一个鸡蛋）对CVD风险的不利作用提供有力支持，尤其是在欧洲研究中。观察性研究的总体证据表明，在欧洲研究人群中，鸡蛋消费与死亡或T2D风险增加无关。也很少有人支持食用鸡蛋在癌症发展中的作用，尽管在一些研究中发现了与某些癌症风险较高的弱关联，主要是病例对照研究。再一次,在欧洲研究中未观察到与癌症风险相关.与其他健康相关结果相关的鸡蛋消费的系统评价和荟萃分析很少。关于每天食用一个以上鸡蛋与疾病风险之间的关联的数据也有限。根据现有证据,一个鸡蛋/天不太可能对整体疾病风险产生不利影响。
