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Abstract：
BACKGROUND: The number and proportion of the elderly population have been continuously increasing in China, leading to the elevated prevalence of chronic diseases and multimorbidity, which ultimately brings heavy burden to society and families. Meanwhile, the status of multimorbidity tends to be more complex in elderly inpatients than community population. In view of the above concerns, this study was designed to investigate the health status of elderly inpatients by analyzing clinical data in Chinese People\'s Liberation Army (PLA) General Hospital from 2008 to 2019, including the constitution of common diseases, comorbidities, the status of multimorbidity, in-hospital death and polypharmacy among elderly inpatients, so as to better understand the diseases spectrum and multimorbidity of elderly inpatients and also to provide supporting evidence for targeted management of chronic diseases in the elderly.
METHODS: A clinical inpatients database was set up by collecting medical records of elderly inpatients from 2008 to 2019 in Chinese PLA General Hospital, focusing on diseases spectrum and characteristics of elderly inpatients. In this study, we collected data of inpatients aged ≥ 65 years old, and further analyzed the constitution of diseases, multimorbidity rates and mortality causes in the past decade. In addition, the prescriptions were also analyzed to investigate the status of polypharmacy in elderly inpatients.
RESULTS: A total of 210,169 elderly patients were hospitalized from January 1st, 2008 to December 31st, 2019. The corresponding number of hospitalizations was 290,833. The average age of the study population was 72.67 years old. Of the total population, 73,493 elderly patients were re-admitted within one year, with the re-hospitalization rate of 25.27%. Malignant tumor, hypertension, ischemic heart disease, diabetes mellitus and cerebrovascular disease were the top 5 diseases. Among the study population, the number of patients with two or more long-term health conditions was 267,259, accounting for 91.89%, with an average of 4.68 diseases. In addition, the average number of medications taken by the study population was 5.4, among which, the proportion of patients taking more than 5 types of medications accounted for 55.42%.
CONCLUSIONS: By analyzing the constitution of diseases and multimorbidity, we found that multimorbidity has turned out to be a prominent problem in elderly inpatients, greatly affecting the process of healthy aging and increasing the burden on families and society. Therefore, multidisciplinary treatment should be strengthened to make reasonable preventive and therapeutic strategies to improve the life quality of the elderly. Meanwhile, more attention should be paid to reasonable medications for elderly patients with multimorbidity to avoid preventable side effects caused by irrational medication therapy.
METHODS: A clinical inpatients database was set up by collecting medical records of elderly inpatients from 2008 to 2019 in Chinese PLA General Hospital, focusing on diseases spectrum and characteristics of elderly inpatients. In this study, we collected data of inpatients aged ≥ 65 years old, and further analyzed the constitution of diseases, multimorbidity rates and mortality causes in the past decade. In addition, the prescriptions were also analyzed to investigate the status of polypharmacy in elderly inpatients.
RESULTS: A total of 210,169 elderly patients were hospitalized from January 1st, 2008 to December 31st, 2019. The corresponding number of hospitalizations was 290,833. The average age of the study population was 72.67 years old. Of the total population, 73,493 elderly patients were re-admitted within one year, with the re-hospitalization rate of 25.27%. Malignant tumor, hypertension, ischemic heart disease, diabetes mellitus and cerebrovascular disease were the top 5 diseases. Among the study population, the number of patients with two or more long-term health conditions was 267,259, accounting for 91.89%, with an average of 4.68 diseases. In addition, the average number of medications taken by the study population was 5.4, among which, the proportion of patients taking more than 5 types of medications accounted for 55.42%.
CONCLUSIONS: By analyzing the constitution of diseases and multimorbidity, we found that multimorbidity has turned out to be a prominent problem in elderly inpatients, greatly affecting the process of healthy aging and increasing the burden on families and society. Therefore, multidisciplinary treatment should be strengthened to make reasonable preventive and therapeutic strategies to improve the life quality of the elderly. Meanwhile, more attention should be paid to reasonable medications for elderly patients with multimorbidity to avoid preventable side effects caused by irrational medication therapy.
摘要：
背景：中国老年人口的数量和比例一直在不断增加，导致慢性病和多发病的患病率上升，最终给社会和家庭带来沉重的负担。同时,老年住院患者的多发病状况往往比社区人群更为复杂.鉴于上述关注,本研究旨在通过分析中国人民解放军总医院2008年至2019年的临床资料，包括常见病的构成，调查老年住院患者的健康状况。合并症,多发病率的状况，老年住院患者的住院死亡和多重用药，从而更好地了解老年住院患者的疾病谱和多发病情况,为老年慢性病的针对性管理提供依据。
方法：收集解放军总医院2008-2019年老年住院患者病历，建立临床住院患者数据库。重点研究老年住院患者的疾病谱和特点。在这项研究中,我们收集了年龄≥65岁的住院患者的数据，并进一步分析了疾病的构成，过去十年的多发病率和死亡率原因。此外,并对处方进行分析,调查老年住院患者的多药用药情况。
结果：从1月1日起，共有210,169名老年患者住院，2008年至12月31日,2019.相应的住院人数为290,833。研究人群的平均年龄为72.67岁。在总人口中,一年内再次收治老年患者73493人,再住院率为25.27%。恶性肿瘤,高血压,缺血性心脏病,糖尿病和脑血管疾病是前5位疾病。在研究人群中，患有两种或两种以上长期健康状况的患者为267,259例，占91.89%，平均4.68种疾病。此外,研究人群平均服用的药物数量为5.4，其中，服用5种以上药物的患者比例为55.42%。
结论：通过分析疾病和多发病的构成，我们发现多发病已经成为老年住院患者的一个突出问题，影响健康老龄化进程,增加家庭和社会负担。因此,加强多学科综合治疗,制定合理的防治策略,提高老年人的生活质量。同时,老年多病患者应注意合理用药，避免因不合理用药而引起的副作用。
方法：收集解放军总医院2008-2019年老年住院患者病历，建立临床住院患者数据库。重点研究老年住院患者的疾病谱和特点。在这项研究中,我们收集了年龄≥65岁的住院患者的数据，并进一步分析了疾病的构成，过去十年的多发病率和死亡率原因。此外,并对处方进行分析,调查老年住院患者的多药用药情况。
结果：从1月1日起，共有210,169名老年患者住院，2008年至12月31日,2019.相应的住院人数为290,833。研究人群的平均年龄为72.67岁。在总人口中,一年内再次收治老年患者73493人,再住院率为25.27%。恶性肿瘤,高血压,缺血性心脏病,糖尿病和脑血管疾病是前5位疾病。在研究人群中，患有两种或两种以上长期健康状况的患者为267,259例，占91.89%，平均4.68种疾病。此外,研究人群平均服用的药物数量为5.4，其中，服用5种以上药物的患者比例为55.42%。
结论：通过分析疾病和多发病的构成，我们发现多发病已经成为老年住院患者的一个突出问题，影响健康老龄化进程,增加家庭和社会负担。因此,加强多学科综合治疗,制定合理的防治策略,提高老年人的生活质量。同时,老年多病患者应注意合理用药，避免因不合理用药而引起的副作用。
