PDF(Pubmed)
Abstract：
BACKGROUND: The prevalence and burden of substance and opium use have increased worldwide over the past decades. In light of rapid population changes in Tehran, we aimed to evaluate the prevalence of opium and other substance use among adult residents in Tehran, Iran.
METHODS: From March 2016 to March 2019, we utilized data from 8 296 participants in the Tehran Cohort Study recruitment phase (TeCS). We calculated the age-sex-weighted prevalence of substance use and the geographic distribution of substance use in Tehran. We also used logistic regression analysis to determine possible determinants of opium use.
RESULTS: We analyzed data from 8 259 eligible participants with complete substance use data and the average age of participants was 53.7 ± 12.75 years. The prevalence of substance use was 5.6% (95% confidence interval [CI]: 4.6- 7.1%). Substance use was more common in males than females (Prevalence: 10.5% [95% CI: 8.6- 12.6%] vs. 0.5% [95% CI: 0.2- 1.2%], respectively). The age-sex weighted prevalence of substance use was 5.4% (95% CI: 4.6-7.1%). Moreover, opium was the most frequently used substance by 95.8% of substance users. Additionally, we found that male gender (Odds ratio [OR]: 12.1, P < 0.001), alcohol intake (OR: 1.3, P = 0.016), and smoking (OR: 8.5, P < 0.001) were independently associated with opium use.
CONCLUSIONS: We found that the prevalence of substance use in Tehran was 5.6%, and opium was the most frequently used substance. In addition, male gender, lower levels of education, alcohol, and tobacco consumption are the main risk factors for substance use in Tehran. Healthcare providers and policymakers can utilize our results to implement preventive strategies to minimize substance use in Tehran.
METHODS: From March 2016 to March 2019, we utilized data from 8 296 participants in the Tehran Cohort Study recruitment phase (TeCS). We calculated the age-sex-weighted prevalence of substance use and the geographic distribution of substance use in Tehran. We also used logistic regression analysis to determine possible determinants of opium use.
RESULTS: We analyzed data from 8 259 eligible participants with complete substance use data and the average age of participants was 53.7 ± 12.75 years. The prevalence of substance use was 5.6% (95% confidence interval [CI]: 4.6- 7.1%). Substance use was more common in males than females (Prevalence: 10.5% [95% CI: 8.6- 12.6%] vs. 0.5% [95% CI: 0.2- 1.2%], respectively). The age-sex weighted prevalence of substance use was 5.4% (95% CI: 4.6-7.1%). Moreover, opium was the most frequently used substance by 95.8% of substance users. Additionally, we found that male gender (Odds ratio [OR]: 12.1, P < 0.001), alcohol intake (OR: 1.3, P = 0.016), and smoking (OR: 8.5, P < 0.001) were independently associated with opium use.
CONCLUSIONS: We found that the prevalence of substance use in Tehran was 5.6%, and opium was the most frequently used substance. In addition, male gender, lower levels of education, alcohol, and tobacco consumption are the main risk factors for substance use in Tehran. Healthcare providers and policymakers can utilize our results to implement preventive strategies to minimize substance use in Tehran.
摘要：
背景：在过去的几十年中，物质和鸦片使用的普遍性和负担在世界范围内有所增加。鉴于德黑兰人口的快速变化，我们的目的是评估德黑兰成年居民中鸦片和其他物质使用的患病率，伊朗。
方法：从2016年3月到2019年3月，我们利用了德黑兰队列研究招募阶段（TeCS）的8296名参与者的数据。我们计算了德黑兰药物使用的年龄性别加权患病率和药物使用的地理分布。我们还使用逻辑回归分析来确定鸦片使用的可能决定因素。
结果：我们分析了8259名符合条件的参与者的数据，这些参与者的平均年龄为53.7±12.75岁。药物使用的患病率为5.6％（95％置信区间[CI]：4.6-7.1％）。男性使用物质比女性更常见(患病率：10.5%[95%CI：8.6-12.6%]vs.0.5%[95%CI：0.2-1.2%]，分别)。药物使用的年龄-性别加权患病率为5.4％（95％CI：4.6-7.1％）。此外，95.8%的药物使用者使用鸦片是最常用的物质。此外,我们发现男性(赔率比[OR]：12.1，P<0.001)，酒精摄入量（OR：1.3，P=0.016），和吸烟（OR：8.5，P<0.001）与鸦片使用独立相关。
结论：我们发现德黑兰的药物使用率为5.6％，鸦片是最常用的物质。此外,男性,教育水平较低，酒精,烟草消费是德黑兰物质使用的主要危险因素。医疗保健提供者和政策制定者可以利用我们的结果来实施预防策略，以最大程度地减少德黑兰的物质使用。
方法：从2016年3月到2019年3月，我们利用了德黑兰队列研究招募阶段（TeCS）的8296名参与者的数据。我们计算了德黑兰药物使用的年龄性别加权患病率和药物使用的地理分布。我们还使用逻辑回归分析来确定鸦片使用的可能决定因素。
结果：我们分析了8259名符合条件的参与者的数据，这些参与者的平均年龄为53.7±12.75岁。药物使用的患病率为5.6％（95％置信区间[CI]：4.6-7.1％）。男性使用物质比女性更常见(患病率：10.5%[95%CI：8.6-12.6%]vs.0.5%[95%CI：0.2-1.2%]，分别)。药物使用的年龄-性别加权患病率为5.4％（95％CI：4.6-7.1％）。此外，95.8%的药物使用者使用鸦片是最常用的物质。此外,我们发现男性(赔率比[OR]：12.1，P<0.001)，酒精摄入量（OR：1.3，P=0.016），和吸烟（OR：8.5，P<0.001）与鸦片使用独立相关。
结论：我们发现德黑兰的药物使用率为5.6％，鸦片是最常用的物质。此外,男性,教育水平较低，酒精,烟草消费是德黑兰物质使用的主要危险因素。医疗保健提供者和政策制定者可以利用我们的结果来实施预防策略，以最大程度地减少德黑兰的物质使用。
