PDF(Pubmed)
Abstract：
Dental sedation plays a pivotal role in alleviating patient anxiety during various procedures. Remimazolam, a benzodiazepine derivative, stands out for its distinctive attributes, particularly its rapid onset of sedation coupled with a brief duration, making it an invaluable option for dental applications. The patient was admitted for the extraction of impacted third molars via patient-controlled sedation and not only demonstrated stable vital signs but also expressed a high level of satisfaction with the procedure. An in-depth analysis of plasma remimazolam concentrations and changes in the Patient State Index revealed negative correlation patterns, highlighting the inherent potential of remimazolam in achieving effective sedation. This expanded research scope aims to provide a more nuanced understanding of the pharmacological responses to remimazolam in dental sedation scenarios. This case report offers valuable insights into the evolving landscape of dental sedation methodologies and paves the way for a more informed and evidence-based approach to the use of remimazolam in patient-controlled sedation.
摘要：
牙科镇静在减轻各种手术期间的患者焦虑中起着关键作用。雷米唑仑,苯二氮卓衍生物，以其独特的属性脱颖而出，特别是它迅速开始镇静，加上短暂的持续时间，使其成为牙科应用的宝贵选择。该患者被允许通过患者控制的镇静作用提取受影响的第三磨牙，不仅表现出稳定的生命体征，而且对该程序也表示了高度的满意。对血浆瑞米唑仑浓度和患者状态指数变化的深入分析揭示了负相关模式，突出了雷米唑仑在实现有效镇静方面的内在潜力。这项扩大的研究范围旨在提供对牙科镇静方案中瑞马唑仑的药理反应的更细致的理解。此病例报告为牙科镇静方法的发展提供了有价值的见解，并为在患者控制的镇静中使用瑞马唑仑的更知情和循证方法铺平了道路。
