PDF(Pubmed)
Abstract：
OBJECTIVE: In the follow-up of patients with thyroid cancer, recurrences are often detected, posing challenges in locating and removing these lesions in a reoperative setting. This study aimed to assess the effectiveness of preoperative ultrasound (US)-guided injection of patent blue (PB) dye into the recurrences to aid in their safe and efficient removal.
METHODS: In this retrospective analysis, we reviewed the records of the patients in a tertiary care centre between February 2019 and March 2023 who underwent US-guided PB injection in the endocrinology outpatient clinic before reoperative neck surgery. The duration between the injection of PB and the initiation of surgery was recorded. The complications and effectiveness of the procedure were evaluated using ultrasonographic, laboratory, surgical, and pathologic records.
RESULTS: We reached 23 consecutive patients with 28 lesions. The recurrences averaged 8.8 mm (4.1-15.6) in size and were successfully stained in all cases. The median time between the PB injection and the incision was 90 (35-210) min. There were no complications related to the dye injection. The blue recurrences were conveniently identified and removed in all cases.
CONCLUSIONS: A preoperative US-guided injection of PB is a safe, readily available and highly effective technique for localising recurrent tumours, even in small lesions within scarred reoperative neck surgeries.
METHODS: In this retrospective analysis, we reviewed the records of the patients in a tertiary care centre between February 2019 and March 2023 who underwent US-guided PB injection in the endocrinology outpatient clinic before reoperative neck surgery. The duration between the injection of PB and the initiation of surgery was recorded. The complications and effectiveness of the procedure were evaluated using ultrasonographic, laboratory, surgical, and pathologic records.
RESULTS: We reached 23 consecutive patients with 28 lesions. The recurrences averaged 8.8 mm (4.1-15.6) in size and were successfully stained in all cases. The median time between the PB injection and the incision was 90 (35-210) min. There were no complications related to the dye injection. The blue recurrences were conveniently identified and removed in all cases.
CONCLUSIONS: A preoperative US-guided injection of PB is a safe, readily available and highly effective technique for localising recurrent tumours, even in small lesions within scarred reoperative neck surgeries.
摘要：
目的：在甲状腺癌患者的随访中，经常检测到复发，在再次手术环境中定位和去除这些病变带来的挑战。这项研究旨在评估术前超声（US）引导下将专利蓝（PB）染料注入复发的有效性，以帮助其安全有效地去除。
方法：在本回顾性分析中，我们回顾了2019年2月至2023年3月在一家三级医疗中心接受美国指导的患者的记录,这些患者在颈部再次手术前在内分泌科门诊接受了美国指导的PB注射.记录注射PB和手术开始之间的持续时间。使用超声检查评估手术的并发症和有效性，实验室,外科,和病理记录。
结果：我们连续23例患者，28个病灶。复发平均大小为8.8mm（4.1-15.6），在所有情况下都成功染色。PB注射到切口之间的中位时间为90（35-210）分钟。无与染料注射相关的并发症。在所有情况下都可以方便地识别和去除蓝色复发。
结论：术前超声引导下注射PB是安全的，用于定位复发性肿瘤的现成且高效的技术，即使在伤痕累累的再次手术颈部手术中的小病变。
方法：在本回顾性分析中，我们回顾了2019年2月至2023年3月在一家三级医疗中心接受美国指导的患者的记录,这些患者在颈部再次手术前在内分泌科门诊接受了美国指导的PB注射.记录注射PB和手术开始之间的持续时间。使用超声检查评估手术的并发症和有效性，实验室,外科,和病理记录。
结果：我们连续23例患者，28个病灶。复发平均大小为8.8mm（4.1-15.6），在所有情况下都成功染色。PB注射到切口之间的中位时间为90（35-210）分钟。无与染料注射相关的并发症。在所有情况下都可以方便地识别和去除蓝色复发。
结论：术前超声引导下注射PB是安全的，用于定位复发性肿瘤的现成且高效的技术，即使在伤痕累累的再次手术颈部手术中的小病变。
