关键词: mastectomy mesenchyme myofibroblasts pseudoangiomatous stromal hyperplasia recurrence: benign surgical excision

Mesh : Humans Male Infant Breast Diseases / diagnostic imaging surgery Breast / diagnostic imaging surgery pathology Hyperplasia / pathology Angiomatosis / diagnosis surgery pathology Neoplasms

来  源:   DOI:10.5604/01.3001.0053.8610

Abstract:
<b><br>Aim:</b> The study was conducted to systematically analyze the recent peer-reviewed literature related to tumoral pseudoangiomatous stromal hyperplasia (PASH) in males.</br> <b><br>Materials and methods:</b> Articles published in peer-reviewed journals of repute from 2012 to 2023 were evaluated for eight variables: 1) the age of the patient, 2) clinical presentation, 3) laterality (unilateral or bilateral), 4) associated breast disorder, 5) the presence of systemic co-morbidity, 6) imaging modalities aiding diagnosis, 7) treatment, and 8) recurrence.</br> <b><br>Results:</b> There were 10 patients ranging in age from 1 year to 67 years (mean: 34.5 years). In 8 cases (80%), there were breast lumps; in 2 cases (20%), there were axillary lumps at presentation. Pain was not a prominent symptom. Six patients (60%) had another breast disorder at presentation and 3 (30%) had significant systemic co-morbidities, including diabetes and renal insufficiency. The greatest dimension of the lumps ranged from 2 cm to 12 cm, with 80% of the lumps being below 5 cm in size. Imaging modalities utilized in evaluation included breast ultrasound (USG), mammograms, computerized tomography (CT), and magnetic resonance imaging (MRI). All the cases were treated surgically, and the final diagnosis was made only after the analysis of the surgical specimen. Recurrence was recorded in 2 (20%) cases.</br> <b><br>Conclusions:</b> Tumoral PASH is a benign myofibroblastic proliferation disorder rarely reported in males. This condition should be considered a differential diagnosis of breast or axillary lumps, and an evaluation should be initiated accordingly. The recommended course of treatment is adequate surgical excision with regular clinical and radiological follow-up.</br>.
摘要:
<b><br>目的:</b>本研究旨在系统分析近期与男性肿瘤假血管瘤性间质增生(PASH)相关的同行评议文献。</br><b><br>材料和方法:</b>对2012年至2023年在同行评审的知名期刊上发表的文章进行了八个变量的评估:1)患者的年龄,2)临床表现,3)侧向性(单边或双边),4)相关的乳房疾病,5)系统性合并症的存在,6)辅助诊断的成像方式,7)治疗,8)复发。</br><b>br>结果:</b>有10例患者年龄从1岁到67岁(平均:34.5岁)。8例(80%)有乳房肿块;在2例(20%)中,报告时有腋窝肿块。疼痛不是突出的症状。6例患者(60%)出现另一种乳房疾病,3例(30%)有明显的全身性合并症,包括糖尿病和肾功能不全。肿块的最大尺寸范围为2厘米至12厘米,80%的肿块大小在5厘米以下。用于评估的成像方式包括乳腺超声(USG),乳房X线照片,计算机断层扫描(CT),磁共振成像(MRI)。所有病例均经手术治疗,只有在对手术标本进行分析后才能做出最终诊断。2例(20%)病例记录复发。</br><b><br>结论:</b>TumanPASH是一种良性肌纤维母细胞增生性疾病,在男性中很少报道。这种情况应被视为乳腺或腋窝肿块的鉴别诊断,并应相应地开始评估。推荐的治疗过程是适当的手术切除,并定期进行临床和放射学随访。</br>.
公众号