Abstract：
Since the Origin of Species, it has been known that evolution depends on what Darwin called the \"strong principle of inheritance.\" Highly accurate replication of cellular phenotype is a universal phenomenon in all of life since LUCA and is often taken for granted as a constant in evolutionary theory. It is not known how self-replication arose during the origin of life. In this report I use the simple mathematics of evolutionary theory to investigate the dynamics of self-replication accuracy and allelic selection. Results indicate that the degree of self-replication accuracy must be greater than a threshold related to the selection coefficients of the alleles in a population in order for evolution to occur. Accurate replication of cellular phenotype and of the molecules involved in genotype/phenotype linkage is necessary for the origin of evolution and may be considered the fundamental principle of life.
摘要：
自从物种起源以来,众所周知，进化取决于达尔文所说的“强大的继承原则”。“自LUCA以来，细胞表型的高度精确复制是所有生命中的普遍现象，并且通常被认为是进化理论中的常数。不知道在生命起源期间自我复制是如何产生的。在本报告中，我使用进化论的简单数学来研究自我复制准确性和等位基因选择的动力学。结果表明，自我复制准确性的程度必须大于与种群中等位基因选择系数相关的阈值，才能发生进化。细胞表型和参与基因型/表型连锁的分子的准确复制对于进化的起源是必要的，并且可以被认为是生命的基本原理。
