Abstract：
UNASSIGNED: Neuroimaging studies have identified alterations in both brain structure and functional connectivity in patients with functional neurological disorder (FND). For many patients, FND emerges from physical precipitating events. Nevertheless, there are a limited number of case series in the literature that describe the clinical presentation and neuroimaging correlates of FND following cerebrovascular disease.
UNASSIGNED: The authors collected data from two clinics in the United Kingdom on 14 cases of acute, improving, or delayed functional neurological symptoms following cerebrovascular events.
UNASSIGNED: Most patients had functional neurological symptoms that were localized to cerebrovascular lesions, and the lesions mapped onto regions known to be part of functional networks disrupted in FND, including the thalamus, anterior cingulate gyrus, insula, and temporoparietal junction.
UNASSIGNED: The findings demonstrate that structural lesions can lead to FND symptoms, possibly explained through changes in relevant mechanistic functional networks.
UNASSIGNED: The authors collected data from two clinics in the United Kingdom on 14 cases of acute, improving, or delayed functional neurological symptoms following cerebrovascular events.
UNASSIGNED: Most patients had functional neurological symptoms that were localized to cerebrovascular lesions, and the lesions mapped onto regions known to be part of functional networks disrupted in FND, including the thalamus, anterior cingulate gyrus, insula, and temporoparietal junction.
UNASSIGNED: The findings demonstrate that structural lesions can lead to FND symptoms, possibly explained through changes in relevant mechanistic functional networks.
摘要：
■神经影像学研究已经确定了功能性神经障碍（FND）患者的大脑结构和功能连接的改变。对于许多患者来说，FND从物理沉淀事件中出现。然而，文献中描述脑血管疾病后FND的临床表现和神经影像学相关因素的病例系列数量有限.
■作者从英国的两个诊所收集了14例急性，改进,或脑血管事件后延迟的功能性神经症状。
■大多数患者有局部为脑血管病变的功能性神经症状，并将病变映射到FND中已知功能网络破坏的区域，包括丘脑,前扣带回，脑岛,和颞顶交界处。
■研究结果表明，结构性病变可导致FND症状，可能通过相关机械功能网络的变化来解释。
■作者从英国的两个诊所收集了14例急性，改进,或脑血管事件后延迟的功能性神经症状。
■大多数患者有局部为脑血管病变的功能性神经症状，并将病变映射到FND中已知功能网络破坏的区域，包括丘脑,前扣带回，脑岛,和颞顶交界处。
■研究结果表明，结构性病变可导致FND症状，可能通过相关机械功能网络的变化来解释。
