PDF(Pubmed)
Abstract：
Poly(vinyl alcohol) is one of the most attractive polymers with a wide range of uses because of its water solubility, biocompatibility, low toxicity, good mechanical properties, and relatively low cost. This review article focuses on recent advances in poly(vinyl alcohol) electrospinning and summarizes parameters of the process (voltage, distance, flow rate, and collector), solution (molecular weight and concentration), and ambient (humidity and temperature) in order to comprehend the influence on the structural, mechanical, and chemical properties of poly(vinyl alcohol)-based electrospun matrices. The importance of poly(vinyl alcohol) electrospinning in biomedical applications is emphasized by exploring a literature review on biomedical applications including wound dressings, drug delivery, tissue engineering, and biosensors. The study also highlights a new promising area of particles formation through the electrospraying of poly(vinyl alcohol). The limitations and advantages of working with different poly(vinyl alcohol) matrices are reviewed, and some recommendations for the future are made to advance this field of study.
摘要：
聚乙烯醇是最有吸引力的聚合物之一,具有广泛的用途,生物相容性，低毒性,良好的机械性能，成本相对较低。本文重点介绍了聚乙烯醇静电纺丝的最新进展，并总结了该过程的参数（电压，距离,流量,和收集器)，溶液（分子量和浓度），和环境（湿度和温度），以了解对结构的影响，机械,基于聚乙烯醇的静电纺丝基质的化学性质。通过探索包括伤口敷料在内的生物医学应用的文献综述，强调了聚（乙烯醇）静电纺丝在生物医学应用中的重要性。药物输送,组织工程,和生物传感器。该研究还强调了通过电喷雾聚乙烯醇形成颗粒的新的有希望的领域。综述了使用不同聚乙烯醇基质的局限性和优点，并提出了一些未来的建议，以推进这一研究领域。
