Abstract：
UNASSIGNED: This study evaluated drug use pattern among hospitalized children with severe acute respiratory infection (SARI) in Nigeria.
UNASSIGNED: A retrospective assessment of prescribed medicines for children aged 13 years and below who were admitted and treated for SARI from 1 January 2016 to 31 December 2018 was conducted. The WHO prescribing indicators and the Index of Rational Drug Prescribing were used to evaluate prescriptions.
UNASSIGNED: A total of 259 patients were included, mostly diagnosed with bronchopneumonia (56%). A summary of WHO-core prescribing indicators showed the average number of drugs per encounter was 3.9, medicines prescribed by generic name was 82.1%, and an encounter with at least an antibiotic was 99.7%. The percentage of drugs prescribed from the Essential Medicine List for children was 79%. The most frequently prescribed pharmacological class of medicines was antibiotics (41.4%). Cephalosporins (40.0%), aminoglycosides (34.1%), and penicillins (21.5%) were the most commonly prescribed antibiotic classes. Gentamicin (34.1%) and cefuroxime (21.5%) were the most commonly prescribed antibiotics.
UNASSIGNED: Drug prescribing for hospitalized children with SARI was suboptimal, especially with regard to polypharmacy, antibiotics, and injection use. Interventions to promote rational use of medicines including antimicrobial stewardship interventions are recommended.
UNASSIGNED: A retrospective assessment of prescribed medicines for children aged 13 years and below who were admitted and treated for SARI from 1 January 2016 to 31 December 2018 was conducted. The WHO prescribing indicators and the Index of Rational Drug Prescribing were used to evaluate prescriptions.
UNASSIGNED: A total of 259 patients were included, mostly diagnosed with bronchopneumonia (56%). A summary of WHO-core prescribing indicators showed the average number of drugs per encounter was 3.9, medicines prescribed by generic name was 82.1%, and an encounter with at least an antibiotic was 99.7%. The percentage of drugs prescribed from the Essential Medicine List for children was 79%. The most frequently prescribed pharmacological class of medicines was antibiotics (41.4%). Cephalosporins (40.0%), aminoglycosides (34.1%), and penicillins (21.5%) were the most commonly prescribed antibiotic classes. Gentamicin (34.1%) and cefuroxime (21.5%) were the most commonly prescribed antibiotics.
UNASSIGNED: Drug prescribing for hospitalized children with SARI was suboptimal, especially with regard to polypharmacy, antibiotics, and injection use. Interventions to promote rational use of medicines including antimicrobial stewardship interventions are recommended.
摘要：
■这项研究评估了尼日利亚严重急性呼吸道感染（SARI）住院儿童的药物使用模式。
对2016年1月1日至2018年12月31日收治并接受SARI治疗的13岁及以下儿童的处方药进行回顾性评估。采用WHO处方指标和合理处方指标对处方进行评价。
■共包括259名患者，主要诊断为支气管肺炎（56%）。世卫组织核心处方指标汇总显示，每次遇到的平均药物数量为3.9，按通用名称处方的药物数量为82.1%，至少有99.7%的抗生素。儿童基本药物清单中规定的药物比例为79%。最常用的药物是抗生素（41.4％）。头孢菌素(40.0%),氨基糖苷类（34.1%），青霉素（21.5％）是最常用的抗生素类别。庆大霉素（34.1％）和头孢呋辛（21.5％）是最常用的抗生素。
■SARI住院儿童的药物处方不理想，特别是在多重用药方面，抗生素,注射使用。建议采取促进合理使用药物的干预措施，包括抗菌药物管理干预措施。
对2016年1月1日至2018年12月31日收治并接受SARI治疗的13岁及以下儿童的处方药进行回顾性评估。采用WHO处方指标和合理处方指标对处方进行评价。
■共包括259名患者，主要诊断为支气管肺炎（56%）。世卫组织核心处方指标汇总显示，每次遇到的平均药物数量为3.9，按通用名称处方的药物数量为82.1%，至少有99.7%的抗生素。儿童基本药物清单中规定的药物比例为79%。最常用的药物是抗生素（41.4％）。头孢菌素(40.0%),氨基糖苷类（34.1%），青霉素（21.5％）是最常用的抗生素类别。庆大霉素（34.1％）和头孢呋辛（21.5％）是最常用的抗生素。
■SARI住院儿童的药物处方不理想，特别是在多重用药方面，抗生素,注射使用。建议采取促进合理使用药物的干预措施，包括抗菌药物管理干预措施。
