Abstract：
OBJECTIVE: To determine the effect of phacoemulsification surgery, which is one of the types of cataract surgery by using ultrasonic power to break up the crystalline lens and clean it with vacuum, on anterior chamber flare (ACF) and choroidal vascular index (CVI).
METHODS: For this cross-sectional study, patients were included if they had cataract with nucleus hardness grade 2 or 3, no systemic inflammatory disease, and not use of anti-inflammatory drugs/prostaglandins preoperatively. ACF using a laser flare meter and CVI in patients underwent uncomplicated phacoemulsification was recorded preoperatively, on the postoperative 1st day, 1st week, and 1st month.
RESULTS: Fifty-six eyes were included. ACF was 9.00 ± 2.90 ph/ms preoperatively. Although ACF increased significantly on postoperative day-1 (39.38 ± 23.31ph/ms) and decreased gradually until the 1st month (14.03 ± 6.03ph/ms) after the operation, it was still significantly higher at the 1st month (p < 0.001). Macular and peripapillary CVI increased significantly on postoperative day-1 (0.64 ± 0.03/0.63 ± 0.05) and week-1 (0.64 ± 0.04/0.62 ± 0.04) (p = 0.01, p < 0.001); the postoperative 1st month was similar to the preoperative one (0.59 ± 0.06/0.58 ± 0.06). The relationship between the change in ACF and the change in CVI was not significant.
CONCLUSIONS: Phacoemulsification causes raises in ACF and CVI due to increased intraocular inflammation. The fact that ACF was significantly higher in postoperative month-1 and CVI returned to its preoperative value suggests that the effect of uncomplicated phacoemulsification surgery on the increase in inflammation in the anterior segment lasts longer than in the posterior segment. These results suggest that ACF and CVI follow-up may be clinically important in the follow-up of postoperative inflammation.
METHODS: For this cross-sectional study, patients were included if they had cataract with nucleus hardness grade 2 or 3, no systemic inflammatory disease, and not use of anti-inflammatory drugs/prostaglandins preoperatively. ACF using a laser flare meter and CVI in patients underwent uncomplicated phacoemulsification was recorded preoperatively, on the postoperative 1st day, 1st week, and 1st month.
RESULTS: Fifty-six eyes were included. ACF was 9.00 ± 2.90 ph/ms preoperatively. Although ACF increased significantly on postoperative day-1 (39.38 ± 23.31ph/ms) and decreased gradually until the 1st month (14.03 ± 6.03ph/ms) after the operation, it was still significantly higher at the 1st month (p < 0.001). Macular and peripapillary CVI increased significantly on postoperative day-1 (0.64 ± 0.03/0.63 ± 0.05) and week-1 (0.64 ± 0.04/0.62 ± 0.04) (p = 0.01, p < 0.001); the postoperative 1st month was similar to the preoperative one (0.59 ± 0.06/0.58 ± 0.06). The relationship between the change in ACF and the change in CVI was not significant.
CONCLUSIONS: Phacoemulsification causes raises in ACF and CVI due to increased intraocular inflammation. The fact that ACF was significantly higher in postoperative month-1 and CVI returned to its preoperative value suggests that the effect of uncomplicated phacoemulsification surgery on the increase in inflammation in the anterior segment lasts longer than in the posterior segment. These results suggest that ACF and CVI follow-up may be clinically important in the follow-up of postoperative inflammation.
摘要：
目的：为了确定超声乳化手术的效果，这是白内障手术的一种类型，通过使用超声电源来打破晶状体并用真空清洁它，前房耀斑（ACF）和脉络膜血管指数（CVI）。
方法：对于这项横断面研究，如果患者患有核硬度2或3级的白内障，没有全身性炎性疾病，术前不使用抗炎药/前列腺素。术前记录使用激光耀斑计的ACF和接受无并发症超声乳化术的患者的CVI，在术后第一天，第一周,和第一个月。
结果：纳入56只眼。术前ACF为9.00±2.90ph/ms。尽管ACF在术后第1天明显升高（39.38±23.31ph/ms），并逐渐下降至术后第1个月（14.03±6.03ph/ms）。在第1个月时仍明显较高（p<0.001）。术后第1天（0.64±0.03/0.63±0.05）和第1周（0.64±0.04/0.62±0.04）的黄斑和乳头周围CVI显着增加（p=0.01，p<0.001）；术后1个月与术前相似（0.59±0.06/0.58±0.06）。ACF变更与CVI变更的关系不显著。
结论：由于眼内炎症增加，白内障超声乳化会导致ACF和CVI升高。ACF在术后1个月明显升高，CVI恢复到其术前值，这一事实表明，简单的超声乳化手术对前段炎症增加的影响比后段持续时间更长。这些结果表明，ACF和CVI随访在术后炎症的随访中可能具有临床重要意义。
方法：对于这项横断面研究，如果患者患有核硬度2或3级的白内障，没有全身性炎性疾病，术前不使用抗炎药/前列腺素。术前记录使用激光耀斑计的ACF和接受无并发症超声乳化术的患者的CVI，在术后第一天，第一周,和第一个月。
结果：纳入56只眼。术前ACF为9.00±2.90ph/ms。尽管ACF在术后第1天明显升高（39.38±23.31ph/ms），并逐渐下降至术后第1个月（14.03±6.03ph/ms）。在第1个月时仍明显较高（p<0.001）。术后第1天（0.64±0.03/0.63±0.05）和第1周（0.64±0.04/0.62±0.04）的黄斑和乳头周围CVI显着增加（p=0.01，p<0.001）；术后1个月与术前相似（0.59±0.06/0.58±0.06）。ACF变更与CVI变更的关系不显著。
结论：由于眼内炎症增加，白内障超声乳化会导致ACF和CVI升高。ACF在术后1个月明显升高，CVI恢复到其术前值，这一事实表明，简单的超声乳化手术对前段炎症增加的影响比后段持续时间更长。这些结果表明，ACF和CVI随访在术后炎症的随访中可能具有临床重要意义。
