Abstract：
BACKGROUND: Segmental bone defects of the mandible result in the complete loss of the affected region. We had incorporated the pressure-reducing device (PRD) designs into the customized mandible prostheses (CMP) and conducted a clinical trial to evaluate this approach.
METHODS: Seven patients were enrolled in this study. We examined the association among the history of radiotherapy, the number of CMP regions, the number of chin regions involved, and CMP exposure.
RESULTS: We included five men and two women with an average age of 55 years. We excised tumors with an average weight of 147.8 g and the average weight of the CMP was 68.5 g. No significant difference between the two weights was noted (p = 0.3882). Three patients received temporary dentures and the CMP remained stable in all patients.
CONCLUSIONS: The use of PRD in CMP may address the previous challenges associated with CMP, but further research is necessary.
METHODS: Seven patients were enrolled in this study. We examined the association among the history of radiotherapy, the number of CMP regions, the number of chin regions involved, and CMP exposure.
RESULTS: We included five men and two women with an average age of 55 years. We excised tumors with an average weight of 147.8 g and the average weight of the CMP was 68.5 g. No significant difference between the two weights was noted (p = 0.3882). Three patients received temporary dentures and the CMP remained stable in all patients.
CONCLUSIONS: The use of PRD in CMP may address the previous challenges associated with CMP, but further research is necessary.
摘要：
背景：下颌骨的节段性骨缺损导致受影响区域的完全丧失。我们已将减压装置（PRD）设计纳入定制的下颌骨假体（CMP）中，并进行了临床试验以评估这种方法。
方法：本研究纳入7例患者。我们检查了放疗史之间的关联，CMP区域的数量，涉及的下巴区域的数量，和CMP曝光。
结果：我们包括5名男性和2名女性，平均年龄为55岁。我们切除了平均重量为147.8g的肿瘤,CMP的平均重量为68.5g。注意到两种重量之间没有显著差异(p=0.3882)。三名患者接受了临时假牙，所有患者的CMP保持稳定。
结论：在CMP中使用PRD可能会解决与CMP相关的先前挑战，但需要进一步的研究。
方法：本研究纳入7例患者。我们检查了放疗史之间的关联，CMP区域的数量，涉及的下巴区域的数量，和CMP曝光。
结果：我们包括5名男性和2名女性，平均年龄为55岁。我们切除了平均重量为147.8g的肿瘤,CMP的平均重量为68.5g。注意到两种重量之间没有显著差异(p=0.3882)。三名患者接受了临时假牙，所有患者的CMP保持稳定。
结论：在CMP中使用PRD可能会解决与CMP相关的先前挑战，但需要进一步的研究。
